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SRD5A1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-31909

Novus Biologicals, part of Bio-Techne
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NBP2-31909
NBP2-31909-25ul

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for SRD5A1 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: GYLQSRYLSHCAVYADDWVTD

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (81%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SRD5A1 Antibody

Immunohistochemistry-Paraffin: SRD5A1 Antibody [NBP2-31909]

Immunohistochemistry-Paraffin: SRD5A1 Antibody [NBP2-31909]

Immunohistochemistry-Paraffin: SRD5A1 Antibody [NBP2-31909] - Staining of human prostate shows strong cytoplasmic positivity in glandular cells.

Applications for SRD5A1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SRD5A1

Steroid 5-alpha-reductase (EC 1.3.99.5) catalyzes the conversion of testosterone into the more potent androgen, dihydrotestosterone (DHT). There are 2 isoforms of the enzyme: SRD5A1 and SRD5A2 (MIM 607306).

Long Name

3-oxo-5-alpha-steroid 4-dehydrogenase 1

Alternate Names

EC 1.3.1.22, S5AR 1, SR type 1

Gene Symbol

SRD5A1

UniProt

Additional SRD5A1 Products

Product Documents for SRD5A1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SRD5A1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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