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SREC-II/SCARF2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-83140

Novus Biologicals, part of Bio-Techne
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NBP1-83140
NBP1-83140-25ul

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: HHDLDNTLNCSFLEPPSGLEQPSPSWSSRASFSSFDTTDEGPVYCVPHEEAPAESRDPEVPTVP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SREC-II/SCARF2 Antibody

Western Blot: SREC-II/SCARF2 Antibody [NBP1-83140]

Western Blot: SREC-II/SCARF2 Antibody [NBP1-83140]

Western Blot: SREC-II/SCARF2 Antibody [NBP1-83140] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumor cells).
Immunocytochemistry/ Immunofluorescence: SREC-II/SCARF2 Antibody [NBP1-83140]

Immunocytochemistry/ Immunofluorescence: SREC-II/SCARF2 Antibody [NBP1-83140]

Immunocytochemistry/Immunofluorescence: SREC-II/SCARF2 Antibody [NBP1-83140] - Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & cytosol.
Western Blot: SREC-II/SCARF2 Antibody [NBP1-83140]

Western Blot: SREC-II/SCARF2 Antibody [NBP1-83140]

Western Blot: SREC-II/SCARF2 Antibody [NBP1-83140] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-553

Applications for SREC-II/SCARF2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SREC-II/SCARF2

The protein encoded by the SCARF2 gene is similar to SCARF1/SREC-I, a scavenger receptor protein that mediates the bindingand degradation of acetylated low density lipoprotein (Ac-LDL). This protein has only little activity of internalizingmodified low density lipoproteins (LDL), but it can interact with SCARF1 through its extracellular domain. Theassociation of this protein with SCARF1 is suppressed by the presence of scavenger ligands. Alternatively splicedtranscript variants encoding distinct isoforms have been reported. (provided by RefSeq)

Long Name

Scavenger Receptor Expressed by Endothelial Cells 2

Alternate Names

SCARF2, SRECII

Gene Symbol

SCARF2

Additional SREC-II/SCARF2 Products

Product Documents for SREC-II/SCARF2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SREC-II/SCARF2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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