SRGAP1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-60649

Novus Biologicals, part of Bio-Techne
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NB100-60649
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Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Human

Applications

Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all SRGAP1 Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 825 and 875 of human SLIT-ROBO Rho GTPase activating protein 1 (Rho GTPase-activating protein 13) using the numbering given in entry NP_065813.1 (GeneID 57522).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SRGAP1 Antibody

Immunoprecipitation: SRGAP1 Antibody [NB100-60649]

Immunoprecipitation: SRGAP1 Antibody [NB100-60649]

Immunoprecipitation: SRGAP1 Antibody [NB100-60649] - Detection of Human SRGAP1 by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-SRGAP1/ARHGAP13 antibody NB100-60649 5Aused for IP at 3 mcg/mg lysate. SRGAP1/ARHGAP13 was also immunoprecipitated by rabbit anti-SRGAP1/ARHGAP13 antibody NB100-60650, which recognizes a downstream epitope. Detection: Chemiluminescence with an exposure time of 1 second.

Applications for SRGAP1 Antibody

Application
Recommended Usage

Immunoprecipitation

2- 5 ug/mg lysate

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: SRGAP1

SRGAP1/ARHGAP13 is a member of the srGAP family of proteins that contain a RhoGAP domain, an SH3 domain, and a Fes/CIP4 homology domain and interact with the intracellular domain of roundabout 1 (Robo1). Robo1 is the receptor for Slit signaling and is involved in neuronal cell migration and axon tract positioning. SRGAP1/ARHGAP13 functions to bind and decrease the level of active Cdc42 and RhoA small GTPases during Slit-Robo signaling. Alternate names for SRGAP1/ARHGAP13 include Rho GTPase-activating protein 13, and KIAA1304.

Alternate Names

ARHGAP13srGAP1, FLJ22166, KIAA1304SLIT-ROBO Rho GTPase-activating protein 1, Rho GTPase-activating protein 13, SLIT-ROBO Rho GTPase activating protein 1

Entrez Gene IDs

57522 (Human)

Gene Symbol

SRGAP1

UniProt

NP_065813.1 (Human)

Additional SRGAP1 Products

Product Documents for SRGAP1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SRGAP1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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