SRGAP1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-13377

Novus Biologicals, part of Bio-Techne
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NBP2-13377
NBP2-13377-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (96%), Rat (94%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all SRGAP1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the amino acids: SPTDRHPDGYLARQRKRGEPPPPVRRPGRTSDGHCPLHPPHALSNSSVDLGSPSLASHPRGLLQNRGLNNDSPERRRRPGHGSLTNISRHDSLKKIDSPPIRRSTSSGQYTGFND

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SRGAP1 Antibody

Immunocytochemistry/ Immunofluorescence: SRGAP1 Antibody [NBP2-13377]

Immunocytochemistry/ Immunofluorescence: SRGAP1 Antibody [NBP2-13377]

Immunocytochemistry/Immunofluorescence: SRGAP1 Antibody [NBP2-13377] - Immunofluorescent staining of human cell line MCF7 shows localization to nuclear speckles.
Immunohistochemistry-Paraffin: SRGAP1 Antibody [NBP2-13377]

Immunohistochemistry-Paraffin: SRGAP1 Antibody [NBP2-13377]

Immunohistochemistry-Paraffin: SRGAP1 Antibody [NBP2-13377] - Staining of human liver shows strong cytoplasmic and nuclear positivity in hepatocytes.

Applications for SRGAP1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SRGAP1

GTPase-activating protein for RhoA and Cdc42 small GTPases. Together with CDC42 seems to be involved in thepathway mediating the repulsive signaling of Robo and Slit proteins in neuronal migration. SLIT2, probably throughinteraction with ROBO1, increases the interaction of SRGAP1 with ROBO1 and inactivates CDC42

Alternate Names

ARHGAP13srGAP1, FLJ22166, KIAA1304SLIT-ROBO Rho GTPase-activating protein 1, Rho GTPase-activating protein 13, SLIT-ROBO Rho GTPase activating protein 1

Gene Symbol

SRGAP1

Additional SRGAP1 Products

Product Documents for SRGAP1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SRGAP1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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