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SSX1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-25157

Novus Biologicals, part of Bio-Techne
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NBP3-25157

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody has been engineered to specifically recognize the recombinant protein SSX1 using the following amino acid sequence: QVEHPQMTFGRLHRIIPKIMPKKPAE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SSX1 Antibody

SSX1 Antibody Immunohistochemistry-Paraffin: SSX1 Antibody [NBP3-25157]

Immunohistochemistry-Paraffin: SSX1 Antibody [NBP3-25157]

Staining of human testis shows strong nuclear positivity in cells in seminiferous ducts.

Applications for SSX1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, we recommend using Heat-Induced Epitope Retrieval (HIER) with a pH level of 6. This optimized retrieval method ensures the best results for your experiments.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SSX1

The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. [provided by RefSeq]

Alternate Names

Cancer/testis antigen 5.1, CT5.1cancer/testis antigen family 5, member 1, MGC150425, protein SSX1, sarcoma, synovial, X-chromosome-related 1, SSRC, synovial sarcoma, X breakpoint 1MGC5162

Gene Symbol

SSX1

Additional SSX1 Products

Product Documents for SSX1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SSX1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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