SSX2 Antibody (CL3202)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-42398

Novus Biologicals, part of Bio-Techne
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NBP2-42398
NBP2-42398-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL3202

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all SSX2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: GKHAWTHRLRERKQLVIYEEISDPEEDDE

Epitope

GKHAWTHRLRERKQL

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for SSX2 Antibody (CL3202)

Immunohistochemistry: SSX2 Antibody (CL3202) [NBP2-42398]

Immunohistochemistry: SSX2 Antibody (CL3202) [NBP2-42398]

Immunohistochemistry: SSX2 Antibody (CL3202) [NBP2-42398] - Staining of human liver shows absence of immunoreactivity in hepatocytes (negative control).
Immunohistochemistry: SSX2 Antibody (CL3202) [NBP2-42398]

Immunohistochemistry: SSX2 Antibody (CL3202) [NBP2-42398]

Immunohistochemistry: SSX2 Antibody (CL3202) [NBP2-42398] - Staining of human testis shows strong nuclear immunoreactivity in a subset of cells in seminiferous tubules.

Applications for SSX2 Antibody (CL3202)

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SSX2

The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene.

Alternate Names

Cancer/testis antigen 5.2, cancer/testis antigen family 5, member 2a, CT5.2a, HD21, HOM-MEL-40, MGC119055, MGC15364, MGC3884, protein SSX2, sarcoma, synovial, X-chromosome-related 2, SSX, SSX2A, SSX2B, synovial sarcoma, X breakpoint 2B, synovial sarcoma, X breakpoint 2CT5.2, Tumor antigen HOM-MEL-40

Gene Symbol

SSX2

UniProt

Q16385 (Human)

Additional SSX2 Products

Product Documents for SSX2 Antibody (CL3202)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SSX2 Antibody (CL3202)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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