ST6GALNAC1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-62649

Novus Biologicals, part of Bio-Techne
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NBP1-62649
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all ST6 Sialyltransferase 1/ST6GALNAC1 Antibodies »

Product Summary for ST6GALNAC1 Antibody

Immunogen

Synthetic peptides corresponding to ST6GALNAC1(ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1) The peptide sequence was selected from the middle region of ST6GALNAC1. Peptide sequence LIKGYEQDVGTRTSFYGFTAFSLTQSLLILGNRGFKNVPLGKDVRYLHFL The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

68 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for ST6GALNAC1 Antibody

Western Blot: ST6GALNAC1 Antibody [NBP1-62649]

Western Blot: ST6GALNAC1 Antibody [NBP1-62649]

Western Blot: ST6GALNAC1 Antibody [NBP1-62649] - Titration: 0.2-1 ug/ml, Positive Control: HepG2 cell lysate.

Applications for ST6GALNAC1 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ST6 Sialyltransferase 1/ST6GALNAC1

Glycosylation of proteins affects cell-cell interaction, interactions with the matrix, and the functions of intracellular molecules. ST6GALNAC1 transfers a sialic acid, N-acetylneuraminic acid (NeuAc), in an alpha-2,6 linkage to O-linked GalNAc residues. The cancer-associated sialyl-Tn (sTn) antigen is formed by ST6GALNAC1-catalyzed sialylation of GalNAc residues on mucins.Glycosylation of proteins affects cell-cell interaction, interactions with the matrix, and the functions of intracellular molecules. ST6GALNAC1 transfers a sialic acid, N-acetylneuraminic acid (NeuAc), in an alpha-2,6 linkage to O-linked GalNAc residues. The cancer-associated sialyl-Tn (sTn) antigen is formed by ST6GALNAC1-catalyzed sialylation of GalNAc residues on mucins (Ikehara et al., 1999 [PubMed 10536037]; Sewell et al., 2006 [PubMed 16319059]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-162 DA594489.1 27-188 163-2334 Y11339.2 49-2220 2335-2530 AK000113.1 1515-1710 2531-2550 Y11339.2 2418-2437

Long Name

ST6 alpha-N-acetylGalactosaminide alpha-2,6-sialyltransferase 1

Alternate Names

Siat7A, ST6GalNAcI, STYI

Gene Symbol

ST6GALNAC1

UniProt

Q9NSC7

Additional ST6 Sialyltransferase 1/ST6GALNAC1 Products

Product Documents for ST6GALNAC1 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for ST6GALNAC1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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