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STAMP2/STEAP4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-56536

Novus Biologicals, part of Bio-Techne
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NBP2-56536
NBP2-56536-25ul

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for STAMP2/STEAP4 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: IRYYVRWRLGNLTVTQAILKKENPFSTSSAWLSD

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for STAMP2/STEAP4 Antibody

Immunocytochemistry/ Immunofluorescence: STAMP2/STEAP4 Antibody [NBP2-56536]

Immunocytochemistry/ Immunofluorescence: STAMP2/STEAP4 Antibody [NBP2-56536]

Immunocytochemistry/Immunofluorescence: STAMP2/STEAP4 Antibody [NBP2-56536] - Staining of human cell line SiHa shows localization to the Golgi apparatus. Antibody staining is shown in green.

Applications for STAMP2/STEAP4 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: STAMP2/STEAP4

STEAP4 is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. It is similar to two other members of the STEAP family, STEAP2 and STEAP3. STEAP4 promotes the reduction of both iron (Fe3+ to Fe2+) and copper (Cu2+ to Cu1+). STEAP4 is highly expressed in placenta, lung, heart and prostate tissues. Furthermore, it is over expressed in prostate cancer cells compared to normal prostate cells. STEAP4 may have a role in cell proliferation and prostrate cancer progression since over expression of STEAP4 in prostate cells significantly increases cell growth and colony formation. At least two isoforms of this protein are known to exist.

Long Name

Six Transmembrane Protein of Prostate 2

Alternate Names

STEAP4, TIARP, TNFAIP9

Gene Symbol

STEAP4

Additional STAMP2/STEAP4 Products

Product Documents for STAMP2/STEAP4 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for STAMP2/STEAP4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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