STAT5a/b Antibody
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-46786
Key Product Details
Species Reactivity
Validated:
Human
Predicted:
Mouse (98%), Rat (98%). Backed by our 100% Guarantee.
Applications
Immunohistochemistry, Immunohistochemistry-Paraffin
Label
Unconjugated
Antibody Source
Polyclonal Rabbit IgG
Concentration
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.
Product Summary for STAT5a/b Antibody
Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: LEAWLQREAQTLQQYRVELAEKHQKTLQLLRKQQTIILDDELIQWKRRQ
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Scientific Data Images for STAT5a/b Antibody
![Immunohistochemistry: STAT5a/b Antibody [NBP2-46786]](https://resources.bio-techne.com/images/products/STAT5a-b-Antibody-Immunohistochemistry-NBP2-46786-img0001.jpg "Immunohistochemistry: STAT5a/b Antibody [NBP2-46786]")
Immunohistochemistry: STAT5a/b Antibody [NBP2-46786]
Immunohistochemistry: STAT5a/b Antibody [NBP2-46786] - Staining of human lymph node shows distinct cytoplasmic positivity in subsets of lymphoid cells.Applications for STAT5a/b Antibody
Application
Recommended Usage
Immunohistochemistry
1:200 - 1:500
Immunohistochemistry-Paraffin
1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Immunogen affinity purified
Formulation
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Concentration
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: STAT5a/b
Signal transduction and activator of transcription 5 (STAT5) is a member of the Jak/STAT signal transduction pathway and is activated by a variety of cytokines (IL22, IL6, IFN-α). STAT5 has two isoforms (A and B) that share 93% amino acid identity and bind the DNA consensus site TTCN3GAA. STAT5 mediates cytokine signaling by acting as a signal transducer in the cytoplasm and, upon phosphorylation, translocates to the nucleus and activates transcription of specific genes. STAT5 is involved in a wide array of biological processes ranging from regulating apoptosis to adult mammary gland proliferation, differentiation and survival.
Long Name
Signal Transducer and Activator of Transcription 5b
Alternate Names
MGF, STAT5, STAT5A signal transducer and activator of transcription 5A
Entrez Gene IDs
6776 (Human)
Gene Symbol
STAT5A
UniProt
Additional STAT5a/b Products
Product Documents for STAT5a/b Antibody
Product Specific Notices for STAT5a/b Antibody
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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