STING/TMEM173 Antibody (2922D) - Azide and BSA Free
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-18817
Recombinant Monoclonal Antibody
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human, Mouse, Rat
Applications
Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Simple Western, Western Blot
Label
Unconjugated
Antibody Source
Monoclonal Rabbit IgG Clone # 2922D
Format
Azide and BSA Free
Concentration
1.0 mg/ml
Product Specifications
Immunogen
Partial recombinant protein made to amino acids 215-379 of human TMEM173/STING (UniProt Q86WV6).
Clonality
Monoclonal
Host
Rabbit
Isotype
IgG
Scientific Data Images for STING/TMEM173 Antibody (2922D) - Azide and BSA Free
Immunohistochemistry: STING/TMEM173 Antibody (2922D) - Azide and BSA Free [NBP3-18817]
Immunohistochemistry: STING/TMEM173 Antibody (2292D) - Azide and BSA Free [NBP3-18817] - STING/TMEM173 was detected in immersion fixed paraffin-embedded sections of mouse lung tissue using Rabbit Anti-Human STING/TMEM173 Monoclonal Antibody at 0.5 ug/mL for 1 hour at room temperature followed by incubation with the Anti-Rabbit IgG VisUCyte™ HRP Polymer Antibody. Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to pneumocytes and alveolar cells. Staining with VisUCyte HRP Polymer Detection Reagents.Applications for STING/TMEM173 Antibody (2922D) - Azide and BSA Free
Application
Recommended Usage
Immunocytochemistry/ Immunofluorescence
3 ug/ml
Immunohistochemistry
0.5 ug/ml
Western Blot
1 - 2 ug/ml
Formulation, Preparation, and Storage
Purification
Protein A or G purified
Formulation
PBS
Format
Azide and BSA Free
Preservative
No Preservative
Concentration
1.0 mg/ml
Stability & Storage
Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C.
Background: STING/TMEM173
References
1. Patel, S., & Jin, L. (2019). TMEM173 variants and potential importance to human biology and disease. Genes and Immunity. https://doi.org/10.1038/s41435-018-0029-9
2. Jounai, N., Kobiyama, K., Takeshita, F., & Ishii, K. J. (2013). Recognition of damage-associated molecular patterns related to nucleic acids during inflammation and vaccination. Frontiers in Cellular and Infection Microbiology. https://doi.org/10.3389/fcimb.2012.00168
3. Xiao, T. S., & Fitzgerald, K. A. (2013). The cGAS-STING Pathway for DNA Sensing. Molecular Cell. https://doi.org/10.1016/j.molcel.2013.07.004
4. Kato, K., Omura, H., Ishitani, R., & Nureki, O. (2017). Cyclic GMP-AMP as an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA. Annual Review of Biochemistry. https://doi.org/10.1146/annurev-biochem-061516-044813
5. Crowl, J. T., Gray, E. E., Pestal, K., Volkman, H. E., & Stetson, D. B. (2017). Intracellular Nucleic Acid Detection in Autoimmunity. Annual Review of Immunology. https://doi.org/10.1146/annurev-immunol-051116-052331
Long Name
Stimulator of Interferon Genes Protein/Transmembrane protein 173
Alternate Names
ERIS, MITA, MPYS, NET23, TMEM173, anti-STING, human STING, mouse STING, STING monoclonal
Gene Symbol
STING1
Additional STING/TMEM173 Products
Product Documents for STING/TMEM173 Antibody (2922D) - Azide and BSA Free
Product Specific Notices for STING/TMEM173 Antibody (2922D) - Azide and BSA Free
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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