SUG1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-57621

Novus Biologicals, part of Bio-Techne
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NBP2-57621
NBP2-57621-25ul
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Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all SUG1 Antibodies »

Product Summary for SUG1 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: VNDKSQNLRRLQAQRNELNAKVRLLREELQLLQEQGSYVGEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLD

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SUG1 Antibody

Immunocytochemistry/ Immunofluorescence: SUG1 Antibody [NBP2-57621]

Immunocytochemistry/ Immunofluorescence: SUG1 Antibody [NBP2-57621]

Immunocytochemistry/Immunofluorescence: SUG1 Antibody [NBP2-57621] - Staining of human cell line U-2 OS shows localization to plasma membrane & cytosol.
Immunohistochemistry-Paraffin: SUG1 Antibody [NBP2-57621]

Immunohistochemistry-Paraffin: SUG1 Antibody [NBP2-57621]

Immunohistochemistry-Paraffin: SUG1 Antibody [NBP2-57621] - Staining of human testis.
Immunohistochemistry-Paraffin: SUG1 Antibody [NBP2-57621]

Immunohistochemistry-Paraffin: SUG1 Antibody [NBP2-57621]

Immunohistochemistry-Paraffin: SUG1 Antibody [NBP2-57621] - Staining of human cerebral cortex, lymph node, skin and testis using Anti-PSMC5 antibody NBP2-57621 (A) shows similar protein distribution across tissues to independent antibody NBP1-87372 (B).
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Applications for SUG1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SUG1

TRIP15 is an essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP. TRIP15 is also involved in early stage of neuronal differentiation via its interaction with NIF3L1.

Alternate Names

MSUG1 protein, p45, p45/SUG26S protease regulatory subunit 8, proteasome (prosome, macropain) 26S subunit, ATPase, 5, proteasome 26S ATPase subunit 5, Proteasome 26S subunit ATPase 5, Proteasome subunit p45, S8, SUG-1, SUG126S proteasome AAA-ATPase subunit RPT6, Tat-binding protein homolog 10, TBP10, thyroid receptor interactor 1, TRIP1Thyroid hormone receptor-interacting protein 1

Gene Symbol

PSMC5

Additional SUG1 Products

Product Documents for SUG1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SUG1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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