Sulfamidase/SGSH Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-83164

Novus Biologicals, part of Bio-Techne
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NBP1-83164
NBP1-83164-25ul
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Key Product Details

Validated by

Orthogonal Validation, Independent Antibodies

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Sulfamidase/SGSH Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: PTGWYKDLRHYYYRARWELYDRSRDPHETQNLATDPRFAQLLEMLRDQLAKWQWETHDPWVCAPDGVLEEKLSPQCQ

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (81%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Sulfamidase/SGSH Antibody

Immunohistochemistry-Paraffin: Sulfamidase/SGSH Antibody [NBP1-83164]

Immunohistochemistry-Paraffin: Sulfamidase/SGSH Antibody [NBP1-83164]

Immunohistochemistry-Paraffin: Sulfamidase/SGSH Antibody [NBP1-83164] - Analysis in human adrenal gland and skeletal muscle tissues. Corresponding SGSH RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: Sulfamidase/SGSH Antibody [NBP1-83164]

Immunohistochemistry-Paraffin: Sulfamidase/SGSH Antibody [NBP1-83164]

Immunohistochemistry-Paraffin: Sulfamidase/SGSH Antibody [NBP1-83164] - Staining of human adrenal gland, duodenum, kidney and skeletal muscle using Anti-SGSH antibody (A) NBP1-83164 shows similar protein distribution across tissues to independent antibody NBP1-83165 (B).
Western Blot: Sulfamidase/SGSH Antibody [NBP1-83164]

Western Blot: Sulfamidase/SGSH Antibody [NBP1-83164]

Western Blot: Sulfamidase/SGSH Antibody [NBP1-83164] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-522
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Applications for Sulfamidase/SGSH Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200-1:500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Sulfamidase/SGSH

SGSH encodes one of several enzymes involved in the lysosomal degradation of heparan sulfate. Mutations in this gene are associated with Sanfilippo syndrome A, one type of the lysosomal storage disease mucopolysaccaridosis III, which results from impaired degradation of heparan sulfate. Transcripts of varying sizes have been reported but their biological validity has not been determined. [provided by RefSeq]

Alternate Names

HSS, MPS3A, SFMD, SGSH

Gene Symbol

SGSH

Additional Sulfamidase/SGSH Products

Product Documents for Sulfamidase/SGSH Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Sulfamidase/SGSH Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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