Sulfatase Modifying Factor 1/SUMF1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-83905

Novus Biologicals, part of Bio-Techne
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NBP1-83905
NBP1-83905-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Sulfatase Modifying Factor 1/SUMF1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: MDAYEVSNTEFEKFVNSTGYLTEAEKFGDSFVFEGMLSEQVKTNIQQAVAAAPWWLPVKGANWRHPEGPDSTILHR

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Sulfatase Modifying Factor 1/SUMF1 Antibody

Immunohistochemistry-Paraffin: Sulfatase Modifying Factor 1/SUMF1 Antibody [NBP1-83905]

Immunohistochemistry-Paraffin: Sulfatase Modifying Factor 1/SUMF1 Antibody [NBP1-83905]

Immunohistochemistry-Paraffin: Sulfatase Modifying Factor 1/SUMF1 Antibody [NBP1-83905] - Staining of human smooth muscle shows strong cytoplasmic positivity in smooth muscle cells.

Applications for Sulfatase Modifying Factor 1/SUMF1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Sulfatase Modifying Factor 1/SUMF1

Sulfatases catalyze the hydrolysis of sulfate esters such as glycosaminoglycans, sulfolipids, and steroid sulfates. C-alpha-formylglycine (FGly), the catalytic residue in the active site of eukaryotic sulfatases, is posttranslationally generated from a cysteine by SUMF1, the FGly-generating enzyme (FGE), in the endoplasmic reticulum (ER). The genetic defect of FGly formation caused by mutations in the SUMF1 gene results in multiple sulfatase deficiency (MSD; MIM 272200), a lysosomal storage disorder (Roeser et al., 2006 [PubMed 16368756]).[supplied by OMIM]

Alternate Names

FGE1

Gene Symbol

SUMF1

Additional Sulfatase Modifying Factor 1/SUMF1 Products

Product Documents for Sulfatase Modifying Factor 1/SUMF1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Sulfatase Modifying Factor 1/SUMF1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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