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SUR-8 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-87831

Novus Biologicals, part of Bio-Techne
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NBP1-87831
NBP1-87831-25ul

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNLHSLPFELALCSKLSIMSIENCPLSHLPPQIVA

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SUR-8 Antibody

Western Blot: SUR-8 Antibody [NBP1-87831]

Western Blot: SUR-8 Antibody [NBP1-87831]

Western Blot: SUR-8 Antibody [NBP1-87831] - Analysis in human cell line T-47d.
Immunocytochemistry/ Immunofluorescence: SUR-8 Antibody [NBP1-87831]

Immunocytochemistry/ Immunofluorescence: SUR-8 Antibody [NBP1-87831]

Immunocytochemistry/Immunofluorescence: SUR-8 Antibody [NBP1-87831] - Staining of human cell line U-251 MG shows localization to nucleoplasm & cytosol. Antibody staining is shown in green.
Western Blot: SUR-8 Antibody [NBP1-87831]

Western Blot: SUR-8 Antibody [NBP1-87831]

Western Blot: SUR-8 Antibody [NBP1-87831] - Analysis in mouse cell line NIH-3T3 and rat cell line NBT-II.

Applications for SUR-8 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Western Blot

0.04-0.4 ug/ml
Application Notes
ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SUR-8

Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes

Alternate Names

KIAA0862FLJ60412, Protein soc-2 homolog, Protein sur-8 homolog, SIAA0862, SOC-2, soc-2 (suppressor of clear, C.elegans) homolog, soc-2 suppressor of clear homolog (C. elegans), SOC2SUR8leucine-rich repeat protein SHOC-2, SUR-8

Gene Symbol

SHOC2

Additional SUR-8 Products

Product Documents for SUR-8 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SUR-8 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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