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Syntrophin alpha 1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-1346

Novus Biologicals, part of Bio-Techne
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NB100-1346

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Bovine (100%), Canine (100%), Porcine (100%). Backed by our 100% Guarantee.

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

Product Specifications

Immunogen

Peptide with sequence ASGRRAPRTGLLE-C corresponding to N-Terminus according to NP_003089.1.

Localization

Membrane-associated. In skeletal muscle, it localizes at the cytoplasmic side of the sarcolemmal membrane and at neuromuscular junctions.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Syntrophin alpha 1 Antibody

Western Blot: Syntrophin alpha 1 Antibody [NB100-1346]

Western Blot: Syntrophin alpha 1 Antibody [NB100-1346]

Western Blot: Syntrophin alpha 1 Antibody [NB100-1346] - Staining (0.1 micrograms/ml) of Human Heart lysate (RIPA buffer, 30 micrograms total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
Western Blot: Syntrophin alpha 1 Antibody [NB100-1346]

Western Blot: Syntrophin alpha 1 Antibody [NB100-1346]

Western Blot: Syntrophin alpha 1 Antibody [NB100-1346] - (0.01ug/ml) staining of Human Muscle lysate (35ug protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence.
Western Blot: Syntrophin alpha 1 Antibody [NB100-1346]

Western Blot: Syntrophin alpha 1 Antibody [NB100-1346]

Western Blot: Syntrophin alpha 1 Antibody [NB100-1346] - (0.01ug/ml) staining of Human Muscle lysate (35ug protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for Syntrophin alpha 1 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:32000

Western Blot

1 - 3 ug/ml
Application Notes
WB: Approx. 60 kDa band observed in human and mouse muscle lysates and in rodent heart lysates (calculated MW of 53.9 kDa band according to human NP_003089.1).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Syntrophin alpha 1

Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes.

Alternate Names

59 kDa dystrophin-associated protein A1 acidic component 1, dJ1187J4.5, LQT12, Pro-TGF-alpha cytoplasmic domain-interacting protein 1, SNT1alpha-1-syntrophin, syntrophin, alpha 1 (dystrophin-associated protein A1, 59kD, acidic component), syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component), Syntrophin-1, TACIP1acidic alpha 1 syntrophin

Entrez Gene IDs

6640 (Human); 20648 (Mouse)

Gene Symbol

SNTA1

Additional Syntrophin alpha 1 Products

Product Documents for Syntrophin alpha 1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Syntrophin alpha 1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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