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Syntrophin alpha 1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NB600-1324

Novus Biologicals, part of Bio-Techne
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NB600-1324

Key Product Details

Species Reactivity

Human, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

9.0 mg/ml

Product Specifications

Immunogen

Synthetic peptide corresponding to the N-terminal sequence of human alpha 1 syntrophin (amino acids 2-18 with C-terminally added lysine) conjugated to KLH.

Reactivity Notes

Cross-reacts with Human and Rat. Expected to cross-react with Mouse due to sequence identity. Not yet tested in other species.

Localization

Membrane-associated. In skeletal muscle, it localizes at the cytoplasmic side of the sarcolemmal membrane and at neuromuscular junctions.

Specificity

Syntrophin alpha 1

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for Syntrophin alpha 1 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Western Blot

1:1000
Application Notes
IHC: Dilution determined by using paraformaldehyde-fixed, Triton X-100 treated, frozen sections of rat skeletal muscle.WB: Dilution determined using a membrane fraction extract of rat skeletal muscle homogenate. Staining of alpha 1 syntrophin is specifically inhibited with alpha 1 syntrophin immunizing peptide. Predicted molecular weight: 60 kDa.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

10mM PBS (pH 7.4)

Format

BSA Free

Preservative

0.9% Sodium Azide

Concentration

9.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Syntrophin alpha 1

Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes.

Alternate Names

59 kDa dystrophin-associated protein A1 acidic component 1, dJ1187J4.5, LQT12, Pro-TGF-alpha cytoplasmic domain-interacting protein 1, SNT1alpha-1-syntrophin, syntrophin, alpha 1 (dystrophin-associated protein A1, 59kD, acidic component), syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component), Syntrophin-1, TACIP1acidic alpha 1 syntrophin

Entrez Gene IDs

362242 (Rat)

Gene Symbol

SNTA1

Additional Syntrophin alpha 1 Products

Product Documents for Syntrophin alpha 1 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Syntrophin alpha 1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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