TAB1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-38458

Novus Biologicals, part of Bio-Techne
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NBP2-38458
NBP2-38458-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (97%), Rat (96%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all TAB1 Antibodies »

Product Summary for TAB1 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: LYVANVGTNRALLCKSTVDGLQVTQLNVDHTTENEDELFRLSQLGLDAGKIKQVGIICGQESTRRIGDYKVKYGYTDIDLLSAAKSKPIIAEPEIHGAQPLDGVTG

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TAB1 Antibody

Immunocytochemistry/ Immunofluorescence: TAB1 Antibody [NBP2-38458]

Immunocytochemistry/ Immunofluorescence: TAB1 Antibody [NBP2-38458]

Immunocytochemistry/Immunofluorescence: TAB1 Antibody [NBP2-38458] - Immunofluorescent staining of human cell line U-2 OS shows localization to nuclear speckles & cytosol.
Immunohistochemistry-Paraffin: TAB1 Antibody [NBP2-38458]

Immunohistochemistry-Paraffin: TAB1 Antibody [NBP2-38458]

Immunohistochemistry-Paraffin: TAB1 Antibody [NBP2-38458] - Staining of human colon shows moderate dot-like nuclear and cytoplasmic positivity in glandular cells.

Applications for TAB1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TAB1

TAB1, TAK1 binding protein, enhances activity of the plasminogen activator inhibitor 1 gene promoter, which is regulated by TGF-beta, and increases the kinase activity of TAK1. TAB1 may function as an activator of the TAK1 MAPKKK in TGF-beta signal transduction (1). Findings suggest that alternative activation pathways contribute to the biological responses of p38alpha to various stimuli. Interaction of p38alpha with TAB1 leads to autophosphorylation and activation of p38alpha (2).

Long Name

TAK1-binding Protein

Alternate Names

MAP3K7IP1

Gene Symbol

TAB1

UniProt

Q15750

Additional TAB1 Products

Product Documents for TAB1 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for TAB1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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