TADA3L Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-90243

Novus Biologicals, part of Bio-Techne
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NBP1-90243
NBP1-90243-25ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Human

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all TADA3L Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LAKEEVSRQELRQRVRMADNEVMDAFRKIMAARQKKRTPTKKEKDQAWKTLKERESILKLLDG

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TADA3L Antibody

Western Blot: TADA3L Antibody [NBP1-90243]

Western Blot: TADA3L Antibody [NBP1-90243]

Western Blot: TADA3L Antibody [NBP1-90243] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumor cells).
Immunocytochemistry/ Immunofluorescence: TADA3L Antibody [NBP1-90243]

Immunocytochemistry/ Immunofluorescence: TADA3L Antibody [NBP1-90243]

Immunocytochemistry/Immunofluorescence: TADA3L Antibody [NBP1-90243] - Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm. Antibody staining is shown in green.
Immunohistochemistry: TADA3L Antibody [NBP1-90243]

Immunohistochemistry: TADA3L Antibody [NBP1-90243]

Immunohistochemistry: TADA3L Antibody [NBP1-90243] - PCAF,TADA3L, and PACS1 protein expression is reduced in human gastric tumor tissue. A tissue microarray (TMA) containing gastric tumor tissue (Tumor) and non-malignant gastric tissue (NM), was immunostained for ADA3. Image collected and cropped by CiteAb from the following publication (https://www.nature.com/articles/s41419-018-0470-8), licensed under a CC-BY license.
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Applications for TADA3L Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50-1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF,Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TADA3L

Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated genetranscription by interacting functionally with the general transcription machinery bound at the basal promoter.Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, therebyrelieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activatoradaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumorsuppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis. At least fouralternatively spliced variants have been found for this gene, but the full-length nature of some variants has not beendetermined. (provided by RefSeq)

Alternate Names

ADA3, ADA3 homolog, alteration/deficiency in activation 3, epididymis secretory sperm binding protein, FLJ20221, FLJ21329, hADA3, NGG1, STAF54, TADA3L, transcriptional adapter 3, Transcriptional adapter 3-like, transcriptional adaptor 3

Gene Symbol

TADA3

Additional TADA3L Products

Product Documents for TADA3L Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TADA3L Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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