Tafazzin/TAZ Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB600-811

Novus Biologicals, part of Bio-Techne
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NB600-811
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Canine (100%), Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all Tafazzin/TAZ Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-HLKTQAEQLHNH corresponding to C-Terminus according to NP_000107.1, NP_851828.1, NP_851829.1, NP_851830.1.

Specificity

This antibody is expected to recognise isoforms 1to 4 (NP_000107.1; NP_851828.1; NP_851829.1; NP_851830.1, respectively).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Tafazzin/TAZ Antibody

Western Blot: Tafazzin/TAZ Antibody [NB600-811]

Western Blot: Tafazzin/TAZ Antibody [NB600-811]

Western Blot: Tafazzin/TAZ Antibody [NB600-811] - (0.3ug/ml) staining of Human Heart lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for Tafazzin/TAZ Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:32000

Western Blot

0.3 - 10 ug/ml
Application Notes
WB: Approx. 28 kDa band observed in human heart lysates (calculated MW of 33.5 kDa band according to NP_000107.1, 30.2 kDa band according to NP_851828.1, 31.7 kDa band according to NP_851829.1 and 28.5 according to NP_851830.1).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Tafazzin/TAZ

The tafazzin protein plays a key role in Barth syndrome. Barth syndrome appears to be a disease of the mitochondria. Tafazzin protrudes into the intermembrane space from both the outer and inner membranes. The tafazzin protein may be associated with cardiolipin, the signature lipid of mitochondria, which has been implicated in other diseases, including those of the heart. Tafazzin may be important in repairing lipids, including cardiolipin, but it is not determined. Tafazzin's association with both the outer membrane and the inner membrane is consistent with its ability to modify a membrane component such as cardiolipin. This antibody is expected to recognise isoforms 1to 4 (NP_000107.1; NP_851828.1; NP_851829.1; NP_851830.1, respectively).

Alternate Names

BTHSEFE, cardiomyopathy, dilated 3A (X-linked), CMD3A, EFE2FLJ27390, G4.5endocardial fibroelastosis 2, LVNCX, Protein G4.5, tafazzin, Taz1, XAP-2

Entrez Gene IDs

6901 (Human)

Gene Symbol

TAFAZZIN

UniProt

NP_000107.1 (Human)

Additional Tafazzin/TAZ Products

Product Documents for Tafazzin/TAZ Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Tafazzin/TAZ Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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