Talin2 Antibody (SR1434)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21636

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-21636-100ul
NBP3-21636-50ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1434

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Talin2 Antibodies »

Product Summary for Talin2 Antibody (SR1434)

Immunogen

A synthesized peptide derived from human Talin2 (Uniprot #: Q9Y4G6)

Specificity

Detects endogenous levels of total Talin2

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

270 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Talin2 Antibody (SR1434)

Western Blot: Talin2 Antibody (SR1434) [NBP3-21636] -

Western Blot: Talin2 Antibody (SR1434) [NBP3-21636] - Western blot analysis using NBP3-21636 in expression HeLa cell lysate.

Applications for Talin2 Antibody (SR1434)

Application
Recommended Usage

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Talin2

Talin2 (talus; Latin for ankle, the shape of a focal adhesion plaque complex) is a 240 kDa cytoplasmic focal adhesion molecule. It likely forms dimers that link integrins to the actin cytoskeleton. Human Talin2 is 2542 amino acids (aa) in length. It contains one globular N-terminal FERM domain that binds integrin cytodomains (aa 88-406), followed by an Ala-rich region (aa 861-1193) and a C-terminal actin-binding domain (aa 2321-2530). Human Talin2 has three potential variants. Two show alternate start sites at Met19 and Met1153, while a third has an alternate start site at Met1608 accompanied by a deletion of aa 1748-1790. Over aa's 977-1183, human Talin2 shares 99% and 97% aa identity with canine and mouse Talin2, respectively.

Alternate Names

ILWEQ, TLN2

Gene Symbol

TLN2

Additional Talin2 Products

Product Documents for Talin2 Antibody (SR1434)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Talin2 Antibody (SR1434)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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