Talin2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-62621

Novus Biologicals, part of Bio-Techne
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NBP2-62621
NBP2-62621-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (98%), Rat (98%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Talin2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: AADLNQSAGEVVHATRGQSGELAAASGKFSDDFDEFLDAGIEMAGQAQTKEDQIQVIGNLKNISMA

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Talin2 Antibody

Immunohistochemistry-Paraffin: Talin2 Antibody [NBP2-62621]

Immunohistochemistry-Paraffin: Talin2 Antibody [NBP2-62621]

Immunohistochemistry-Paraffin: Talin2 Antibody [NBP2-62621] - Staining of human cerebral cortex shows high expression.
Immunohistochemistry-Paraffin: Talin2 Antibody [NBP2-62621]

Immunohistochemistry-Paraffin: Talin2 Antibody [NBP2-62621]

Immunohistochemistry-Paraffin: Talin2 Antibody [NBP2-62621] - Immunohistochemistry analysis in human cerebral cortex and pancreas tissues using Anti-TLN2 antibody. Corresponding TLN2 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: Talin2 Antibody [NBP2-62621]

Immunohistochemistry-Paraffin: Talin2 Antibody [NBP2-62621]

Immunohistochemistry-Paraffin: Talin2 Antibody [NBP2-62621] - Staining of human pancreas shows low expression as expected.

Applications for Talin2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Talin2

Talin2 (talus; Latin for ankle, the shape of a focal adhesion plaque complex) is a 240 kDa cytoplasmic focal adhesion molecule. It likely forms dimers that link integrins to the actin cytoskeleton. Human Talin2 is 2542 amino acids (aa) in length. It contains one globular N-terminal FERM domain that binds integrin cytodomains (aa 88-406), followed by an Ala-rich region (aa 861-1193) and a C-terminal actin-binding domain (aa 2321-2530). Human Talin2 has three potential variants. Two show alternate start sites at Met19 and Met1153, while a third has an alternate start site at Met1608 accompanied by a deletion of aa 1748-1790. Over aa's 977-1183, human Talin2 shares 99% and 97% aa identity with canine and mouse Talin2, respectively.

Alternate Names

ILWEQ, TLN2

Gene Symbol

TLN2

Additional Talin2 Products

Product Documents for Talin2 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Talin2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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