TAO Kinase 1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-50166

Novus Biologicals, part of Bio-Techne
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NBP1-50166
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat, Porcine, Bat, Bovine, Canine, Chicken, Equine, Hamster, Monkey, Primate, Rabbit, Xenopus

Predicted:

Avian (100%), Opossum (100%). Backed by our 100% Guarantee.

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all TAO Kinase 1 Antibodies »

Product Specifications

Immunogen

Synthetic 17 amino acid peptide from C-Terminus of human TAO Kinase 1.

Epitope

C-Terminus

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (100%), Zebrafish (88%).

Specificity

Human TAO Kinase 1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for TAO Kinase 1 Antibody - BSA Free

Immunohistochemistry-Paraffin: TAO Kinase 1 Antibody - BSA Free [NBP1-50166]

Immunohistochemistry-Paraffin: TAO Kinase 1 Antibody - BSA Free [NBP1-50166]

Immunohistochemistry-Paraffin: TAO Kinase 1 Antibody - BSA Free [NBP1-50166] - Analysis of anti-TAOK1 antibody with human brain, cortex at concentration 5 ug/ml.
Immunohistochemistry-Paraffin: TAO Kinase 1 Antibody - BSA Free [NBP1-50166]

Immunohistochemistry-Paraffin: TAO Kinase 1 Antibody - BSA Free [NBP1-50166]

Immunohistochemistry-Paraffin: TAO Kinase 1 Antibody - BSA Free [NBP1-50166] - Analysis of anti-TAOK1 antibody with human brain, cortex at concentration 5 ug/ml.

Applications for TAO Kinase 1 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100 - 1:2000

Immunohistochemistry-Paraffin

5 ug/ml
Application Notes
IHC-P: Requires pretreatment with Proteinase K..

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: TAO Kinase 1

TAOK1, a member of the Ste20 kinase family, is a TAO type protein kinase that acts as an upstream activator to MARK by phosphorylation. When activated, MARK enhances microtubule dynamics and leads to phosphorylation and detachment of tau or equivalent MAPs from microtubules. Overexpression of MARK eventually leads to microtubule breakdown and cell death, but in neuronal cells the primary effect is to allow the development of neurites during differentiation.

Long Name

Serine/threonine-protein kinase TAO1

Alternate Names

hKFC-B, hTAOK1, KIAA1361, MAP3K16, MARK Kinase, MARKK, PSK-2, PSK2, TAOK1

Entrez Gene IDs

57551 (Human)

Gene Symbol

TAOK1

UniProt

Q7L7X3 (Human)

Additional TAO Kinase 1 Products

Product Documents for TAO Kinase 1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TAO Kinase 1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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