TAO2 Antibody (2E2)

Novus Biologicals, part of Bio-Techne | Catalog # H00009344-M03

Novus Biologicals, part of Bio-Techne
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H00009344-M03-100ug
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 2E2

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all TAO2 Antibodies »

Product Specifications

Immunogen

TAOK2 (AAH51798, 831 a.a. ~ 930 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. ELQCRQYKRKMLLARHSLDQDLLREDLNKKQTQKDLECALLLRQHEATRELELRQLQAVQRTRAELTRLQHQTELGNQLEYNKRREQELRQKHAAQVRQQ

Reactivity Notes

Human. Other species not tested.

Specificity

TAOK2 (2E2)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Scientific Data Images for TAO2 Antibody (2E2)

Immunohistochemistry-Paraffin: TAO2 Antibody (2E2) [H00009344-M03]

Immunohistochemistry-Paraffin: TAO2 Antibody (2E2) [H00009344-M03]

Immunohistochemistry-Paraffin: TAO2 Antibody (2E2) [H00009344-M03] - Analysis of monoclonal antibody to TAOK2 on formalin-fixed paraffin-embedded human kidney. Antibody concentration 3 ug/ml
ELISA: TAO2 Antibody (2E2) [H00009344-M03]

ELISA: TAO2 Antibody (2E2) [H00009344-M03]

ELISA: TAO2 Antibody (2E2) [H00009344-M03] - Detection limit for recombinant GST tagged TAOK2 is approximately 1ng/ml as a capture antibody.

Applications for TAO2 Antibody (2E2)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactive against recombinant protein for Western Blot. Has also been used for immunohistochemistry (paraffin) and ELISA.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: TAO2

In vitro, TAO (thousand and one amino acid) protein kinase 2 (TAO2) activates MAP/ERK kinases (MEKs) 3, 4, and 6 toward their substrates p38 MAP kinase JNK/SAPK (Chen et al., 1999; Chen and Cobb, 2001). This and more recent work has led to the proposal that the TAO protein kinases play an essential role in signaling from physiological agonists to the stress-responsive p38 MAPKs (Chen et al., 2003). Autophosphorylation of TAO may play a role in the mechanism of TAO activation. The MEK binding domain of TAO is autophosphorylated on both serine and threonine residues and Ser181 is located within this domain.

Long Name

Serine/Threonine-protein Kinase TAO2

Alternate Names

KFC-C, MAP3K17, PSK1, TAO1, TAOK2

Entrez Gene IDs

9344 (Human)

Gene Symbol

TAOK2

UniProt

AAH51798 (Human)

Additional TAO2 Products

Product Documents for TAO2 Antibody (2E2)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TAO2 Antibody (2E2)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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