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TARBP1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-86902

Novus Biologicals, part of Bio-Techne
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NBP1-86902
NBP1-86902-25ul

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for TARBP1 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: MNELNSVSDLDRCHLYLMVLTELINLHLKVGWKRGNPIWRVISLLKNASIQHLQEMDSGQEPTVGSQIQRVVSMAALAMVCEAIDQKPELQLDSLHAG

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TARBP1 Antibody

Immunocytochemistry/ Immunofluorescence: TARBP1 Antibody [NBP1-86902]

Immunocytochemistry/ Immunofluorescence: TARBP1 Antibody [NBP1-86902]

Immunocytochemistry/Immunofluorescence: TARBP1 Antibody [NBP1-86902] - Staining of human cell line A-431 shows localization to nuclear speckles.
Immunohistochemistry-Paraffin: TARBP1 Antibody [NBP1-86902]

Immunohistochemistry-Paraffin: TARBP1 Antibody [NBP1-86902]

Immunohistochemistry-Paraffin: TARBP1 Antibody [NBP1-86902] - Staining of human duodenum shows cytoplasmic positivity in glandular cells.

Applications for TARBP1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TARBP1

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. This element forms a stable stem-loop structure and can be bound by either the protein encoded by this gene or by RNA polymerase II. This protein may act to disengage RNA polymerase II from TAR during transcriptional elongation. Alternatively spliced transcripts of this gene may exist, but their full-length natures have not been determined.

Alternate Names

EC 2.1.1.-, FLJ30482, TAR (HIV-1) RNA binding protein 1, TAR RNA loop binding protein, TAR RNA-binding protein 1, TAR RNA-binding protein of 185 kDa, tardbp1, TRM3probable methyltransferase TARBP1, TRP-185TAR (HIV) RNA binding protein 1, TRP185TAR (HIV) RNA-binding protein 1

Gene Symbol

TARBP1

Additional TARBP1 Products

Product Documents for TARBP1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TARBP1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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