TAS2R10 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-25171

Novus Biologicals, part of Bio-Techne
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NBP3-25171
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all TAS2R10 Antibodies »

Product Specifications

Immunogen

This antibody has been engineered to specifically recognize the recombinant protein TAS2R10 using the following amino acid sequence: FAYIAKILNDYKMKNDTVWDLNMYK

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TAS2R10 Antibody

TAS2R10 Antibody Immunocytochemistry/Immunofluorescence: TAS2R10 Antibody [NBP3-25171]

Immunocytochemistry/Immunofluorescence: TAS2R10 Antibody [NBP3-25171]

Staining of human cell line HeLa shows localization to plasma membrane, actin filaments & vesicles.

Applications for TAS2R10 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 µg/ml
Application Notes
For ICC/IF, we recommend using a combination of PFA and Triton X-100. This will give you the optimal results for your experiments.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TAS2R10

TAS2R10 product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13. FUNCTION: Gustducin-coupled strychnine receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells. MISCELLANEOUS: Several bitter taste receptors are expressed in a single taste receptor cell. Useful Links; The Human Olfactory Data Exploratorium: HORDE; Olfactory Receptor Data Base: ORDB; Transmembrane Analysis: TM analysis

Alternate Names

MGC126811, T2R10, T2R10 MGC126813, Taste receptor family B member 2, taste receptor, family B, member 2, taste receptor, type 2, member 10, TRB2taste receptor type 2 member 10

Gene Symbol

TAS2R10

Additional TAS2R10 Products

Product Documents for TAS2R10 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TAS2R10 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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