TAS2R38 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-33711

Novus Biologicals, part of Bio-Techne
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NBP2-33711
NBP2-33711-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all TAS2R38 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: NAKLRRAVMTILLWAQSSLKVRADHKADSRTL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TAS2R38 Antibody

Immunohistochemistry-Paraffin: TAS2R38 Antibody [NBP2-33711]

Immunohistochemistry-Paraffin: TAS2R38 Antibody [NBP2-33711]

Immunohistochemistry-Paraffin: TAS2R38 Antibody [NBP2-33711] - Staining of human rectum shows strong cytoplasmic and membranous positivity in glandular cells.

Applications for TAS2R38 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TAS2R38

The STAS2R38 gene encodes a 333 amino acid long, 37 kDA taste receptor type 2 member 38 protein that obtains the ability to identify the perception of bitterness as it obtains the capabilities of tasting glucosinolates. Additionally, many believe that this receptor has the ability to stimulate alpha gustducin to regulate PLC-beta-2 activation. In doing so, it would lead to the gating of TRPM5. Therefore, the STAS2R38 gene is involved in taste transduction and bitter taste signaling. It has been researched regarding its role in thyroiditis, dental caries, nicotine dependence, motion sickness, phenylthiocarbamide tasting, coronary heart disease, alcoholism, and twining.

Alternate Names

PTCphenylthiocarbamide tasting, T2R38, T2R61PTC bitter taste receptor, taste receptor type 2 member 38, Taste receptor type 2 member 61, taste receptor, type 2, member 38

Gene Symbol

TAS2R38

UniProt

P59533 (Human)

Additional TAS2R38 Products

Product Documents for TAS2R38 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TAS2R38 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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