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Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Validated:

Human

Applications

Immunoprecipitation, Western Blot (Negative)

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

Product Summary for TBC1D9 Antibody

Immunogen

The immunogen recognized by this antibody maps to a region between residue 1118 and the C-terminus (residue 1168) of human TBC1 domain family, member 9 using the numbering given in entry NP_055945.1 (GeneID 23158).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

143 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for TBC1D9 Antibody

Immunoprecipitation: TBC1D9 Antibody [NB100-55321]

Immunoprecipitation: TBC1D9 Antibody [NB100-55321]

Immunoprecipitation: TBC1D9 Antibody [NB100-55321] - Detection of Human TBC1D9 by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from 293T cells prepared using NETN lysis buffer.

Applications for TBC1D9 Antibody

Application
Recommended Usage

Immunoprecipitation

2-10 ug/mg lysate
Application Notes
At a dilution of 1:1,000, A301-028A performs well with enriched sources (e.g. immunoprecipitation reactions) of TBC1D9/MDR1. Has not performed reliably for whole cell lysate.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: TBC1D9

TBC1D9, also known as MDR1 (multidrug resistance 1), is a P-glycoprotein implicated in the mechanism of multidrug resistance to chemotherapeutic agents. TBC1D9 functions as an energy-dependent membrane efflux pump for lipophilic compounds.

Alternate Names

KIAA0882TBC1 domain family member 9, MDR1, TBC1 domain family member 9A, TBC1 domain family, member 9, TBC1 domain family, member 9 (with GRAM domain), TBC1D9A

Entrez Gene IDs

23158 (Human)

Gene Symbol

TBC1D9

UniProt

Additional TBC1D9 Products

Product Documents for TBC1D9 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TBC1D9 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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