Tbp7 Antibody (SR1808)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22626

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-22626-100ul
NBP3-22626-50ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1808

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Tbp7 Antibodies »

Product Summary for Tbp7 Antibody (SR1808)

Immunogen

A synthesized peptide derived from human Tbp7 (Uniprot #: P43686)

Specificity

Detects endogenous levels of total Tbp7

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

47 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Tbp7 Antibody (SR1808)

Western Blot: Tbp7 Antibody (SR1808) [NBP3-22626] -

Western Blot: Tbp7 Antibody (SR1808) [NBP3-22626] - Western blot analysis using NBP3-22626 in HeLa cell lysate.

Applications for Tbp7 Antibody (SR1808)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Tbp7

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit has been shown to interact with an orphan member of the nuclear hormone receptor superfamily highly expressed in liver, and with gankyrin, a liver oncoprotein. Two transcript variants encoding different isoforms have been identified.

Alternate Names

MB67 interacting protein, MGC13687,26S protease regulatory subunit 6B, MGC23214, MGC8570, protease 26S subunit 6, proteasome (prosome, macropain) 26S subunit, ATPase, 4,26S proteasome AAA-ATPase subunit RPT3, Proteasome 26S subunit ATPase 4, S6Tat-binding protein 7, TBP-7MB67-interacting protein, TBP7MIP224

Gene Symbol

PSMC4

Additional Tbp7 Products

Product Documents for Tbp7 Antibody (SR1808)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Tbp7 Antibody (SR1808)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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