Tbp7 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-20581

Novus Biologicals, part of Bio-Techne
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NBP2-20581
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%), Mouse (100%), Rat (100%), Rhesus Macaque (100%), Xenopus (98%), Zebrafish (98%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Tbp7 Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human Tbp7. The exact sequence is proprietary.

Reactivity Notes

Xenopus laevis (98%).

Localization

Cytoplasm; Nucleus

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

47 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Tbp7 Antibody

Western Blot: Tbp7 Antibody [NBP2-20581]

Western Blot: Tbp7 Antibody [NBP2-20581]

Western Blot: Tbp7 Antibody [NBP2-20581] - Sample (30 ug of whole cell lysate) A: JurKat 10% SDS PAGE gel, diluted at 1:1000.
Immunocytochemistry/ Immunofluorescence: Tbp7 Antibody [NBP2-20581]

Immunocytochemistry/ Immunofluorescence: Tbp7 Antibody [NBP2-20581]

Immunocytochemistry/Immunofluorescence: Tbp7 Antibody [NBP2-20581] - Immunofluorescence analysis of paraformaldehyde-fixed A431, using antibody at 1:200 dilution.
Immunohistochemistry-Paraffin: Tbp7 Antibody [NBP2-20581]

Immunohistochemistry-Paraffin: Tbp7 Antibody [NBP2-20581]

Immunohistochemistry-Paraffin: Tbp7 Antibody [NBP2-20581] - Paraffin-embedded Mahlarvu xenograft. PSMC4 antibody dilution: 1:500.

Applications for Tbp7 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Tbp7

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit has been shown to interact with an orphan member of the nuclear hormone receptor superfamily highly expressed in liver, and with gankyrin, a liver oncoprotein. Two transcript variants encoding different isoforms have been identified. [provided by RefSeq]

Alternate Names

MB67 interacting protein, MGC13687,26S protease regulatory subunit 6B, MGC23214, MGC8570, protease 26S subunit 6, proteasome (prosome, macropain) 26S subunit, ATPase, 4,26S proteasome AAA-ATPase subunit RPT3, Proteasome 26S subunit ATPase 4, S6Tat-binding protein 7, TBP-7MB67-interacting protein, TBP7MIP224

Gene Symbol

PSMC4

UniProt

P43686 (Human)

Additional Tbp7 Products

Product Documents for Tbp7 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Tbp7 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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