TC10 Antibody (SR1384)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22043

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NBP3-22043-100ul
NBP3-22043-50ul
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Species Reactivity

Validated:

Human, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1384

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all TC10 Antibodies »

Product Summary for TC10 Antibody (SR1384)

Immunogen

A synthesized peptide derived from human TC10 (Uniprot #: P17081)

Specificity

Detects endogenous levels of total TC10

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

25 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for TC10 Antibody (SR1384)

Western Blot: TC10 Antibody (SR1384) [NBP3-22043] -

Western Blot: TC10 Antibody (SR1384) [NBP3-22043] - Western blot analysis using NBP3-22043 in 293T cell lysate.

Applications for TC10 Antibody (SR1384)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TC10

TC10 is a member of the Rho family of GTP-binding proteins and is closely related to Cdc42 and Rac 1. Cycling between inactive and active GTP-bound state, active TC10 can directly interact with Cdc42 kinase, p21-activated protein kinases as well as other kinases (1). Constitutive expression of active TC10 mutants (TC10/Q75L) in fibroblast decrease actin stress fiber and formation of plasma membrane microspikes, while wild type TC10 has no effect on fibroblast cell morphology (2). Mostly expressed in adipose and muscle tissues, TC10 has been found to be activated by C3G (from the insulin pathway) in adipocytes (3).

Alternate Names

ARHQTC10A, ras homolog gene family, member Q, Ras-like protein family member 7A, Ras-like protein TC10, RAS-like, family 7, member A, rho-related GTP-binding protein RhoQ, TC10RASL7A

Gene Symbol

RHOQ

Additional TC10 Products

Product Documents for TC10 Antibody (SR1384)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for TC10 Antibody (SR1384)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.