TC10 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00023433-B01P

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Mouse IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all TC10 Antibodies »

Product Specifications

Immunogen

RHOQ (NP_036381.2, 1 a.a. - 205 a.a.) full-length human protein. MAHGPGALMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVSVTVGGKQYLLGLYDTAGQEDYDRLRPLSYPMTDVFLICFSVVNPASFQNVKEEWVPELKEYAPNVPFLLIGTQIDLRDDPKTLARLNDMKEKPICVEQGQKLAKEIGACCYVECSALTQKGLKTVFDEAIIAILTPKKHTVKKRIGSRCINCCLIT

Clonality

Polyclonal

Host

Mouse

Isotype

IgG

Scientific Data Images for TC10 Antibody

Western Blot: TC10 Antibody [H00023433-B01P]

Western Blot: TC10 Antibody [H00023433-B01P]

Western Blot: TC10 Antibody [H00023433-B01P] - Analysis of RHOQ expression in transfected 293T cell line by RHOQ polyclonal antibody. Lane 1: RHOQ transfected lysate(22.55 KDa). Lane 2: Non-transfected lysate.
Immunocytochemistry/ Immunofluorescence: TC10 Antibody [H00023433-B01P]

Immunocytochemistry/ Immunofluorescence: TC10 Antibody [H00023433-B01P]

Immunocytochemistry/Immunofluorescence: TC10 Antibody [H00023433-B01P] - Analysis of purified antibody to RHOQ on HeLa cell. (antibody concentration 10 ug/ml)

Applications for TC10 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
This antibody is useful for Western Blot, Functional, Immunofluorescence

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: TC10

TC10 is a member of the Rho family of GTP-binding proteins and is closely related to Cdc42 and Rac 1. Cycling between inactive and active GTP-bound state, active TC10 can directly interact with Cdc42 kinase, p21-activated protein kinases as well as other kinases (1). Constitutive expression of active TC10 mutants (TC10/Q75L) in fibroblast decrease actin stress fiber and formation of plasma membrane microspikes, while wild type TC10 has no effect on fibroblast cell morphology (2). Mostly expressed in adipose and muscle tissues, TC10 has been found to be activated by C3G (from the insulin pathway) in adipocytes (3).

Alternate Names

ARHQTC10A, ras homolog gene family, member Q, Ras-like protein family member 7A, Ras-like protein TC10, RAS-like, family 7, member A, rho-related GTP-binding protein RhoQ, TC10RASL7A

Gene Symbol

RHOQ

UniProt

NP_036381.2 (Human)

Additional TC10 Products

Product Documents for TC10 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for TC10 Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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