TCF-2/HNF-1 beta Antibody (SR2149)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21992

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-21992-100ul
NBP3-21992-50ul
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR2149

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all TCF-2/HNF-1 beta Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human TCF-2/HNF-1 beta (Uniprot #: P35680)

Specificity

Detects endogenous levels of total TCF-2/HNF-1 beta

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

70 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for TCF-2/HNF-1 beta Antibody (SR2149)

Western Blot: TCF-2/HNF-1 beta Antibody (SR2149) [NBP3-21992] -

Western Blot: TCF-2/HNF-1 beta Antibody (SR2149) [NBP3-21992] - Western blot analysis using NBP3-21992 in SK-OV-3 cell lysate.

Applications for TCF-2/HNF-1 beta Antibody (SR2149)

Application
Recommended Usage

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TCF-2/HNF-1 beta

TCF2 encodes transcription factor 2, a liver-specific factor of the homeobox-containing basic helix-turn-helix family. The TCF2 protein is believed to form heterodimers with another liver-specific member of this transcription factor family, TCF1; depending on the TCF2 isoform, the result may be to activate or inhibit transcription of target genes. Mutation of TCF2 that disrupts normal function has been identified as the cause of MODY5 (Maturity-Onset of Diabetes, Type 5). A third human transcript variant is believed to exist based on such a variant in the rat: however, to date such an mRNA species has not been isolated.

Long Name

Transcription Factor 2

Alternate Names

HNF-1 beta, HNF1B, HNF2, LF-B3, MODY5, TCF2, VHNF1

Gene Symbol

HNF1B

Additional TCF-2/HNF-1 beta Products

Product Documents for TCF-2/HNF-1 beta Antibody (SR2149)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TCF-2/HNF-1 beta Antibody (SR2149)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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