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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # TCL1/2078

Concentration

0.2 mg/ml

Product Specifications

Immunogen

Recombinant human TCL1A protein fragment (around aa 2-109) (exact sequence is proprietary) (Uniprot: P56279)

Localization

Nuclear and Cytoplasmic

Marker

T-Cell Marker

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Theoretical MW

14 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP2-75750)

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.

Scientific Data Images for TCL1A Antibody (TCL1/2078)

Immunohistochemistry-Paraffin: TCL1A Antibody (TCL1/2078) [NBP2-75747]

Immunohistochemistry-Paraffin: TCL1A Antibody (TCL1/2078) [NBP2-75747]

Immunohistochemistry-Paraffin: TCL1A Antibody (TCL1/2078) [NBP2-75747] - Formalin-fixed, paraffin-embedded human Tonsil stained with TCL1 Mouse Monoclonal Antibody (TCL1/2078).
Immunohistochemistry-Paraffin: TCL1A Antibody (TCL1/2078) [NBP2-75747]

Immunohistochemistry-Paraffin: TCL1A Antibody (TCL1/2078) [NBP2-75747]

Immunohistochemistry-Paraffin: TCL1A Antibody (TCL1/2078) [NBP2-75747] - Formalin-fixed, paraffin-embedded human Spleen stained with TCL1 Mouse Monoclonal Antibody (TCL1/2078).
Protein Array: TCL1A Antibody (TCL1/2078) [NBP2-75747]

Protein Array: TCL1A Antibody (TCL1/2078) [NBP2-75747]

Protein Array: TCL1A Antibody (TCL1/2078) [NBP2-75747] - Analysis of Protein Array containing more than 19,000 full-length human proteins using TCL1A Antibody (TCL1/2078). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5.

Applications for TCL1A Antibody (TCL1/2078)

Application
Recommended Usage

Immunohistochemistry-Paraffin

1-2 ug/ml
Application Notes
Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes.
Optimal dilution for a specific application should be determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10 mM PBS with 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: TCL1A

Enhances the phosphorylation and activation of AKT1, AKT2 and AKT3. Promotes nuclear translocation of AKT1. Enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival

Long Name

T Cell Leukemia Protein 1A

Alternate Names

TCL1-PEN

Gene Symbol

TCL1A

UniProt

Additional TCL1A Products

Product Documents for TCL1A Antibody (TCL1/2078)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TCL1A Antibody (TCL1/2078)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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