TCP1-beta Antibody (F39 P7 F11)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-66591

Novus Biologicals, part of Bio-Techne
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NBP2-66591
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Key Product Details

Species Reactivity

Human, Mouse, Rat, Xenopus

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # F39 P7 F11

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all TCP1-beta Antibodies »

Product Specifications

Immunogen

Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with a synthetic peptide derived from the C-terminal of the TCP1-beta protein (Uniprot: P47207) and mouse myeloma Ag8563 cells.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Scientific Data Images for TCP1-beta Antibody (F39 P7 F11)

TCP1-beta Antibody (F39 P7 F11)

Immunohistochemistry: TCP1-beta Antibody (F39 P7 F11) [NBP2-66591] -

Immunohistochemistry: TCP1-beta Antibody (F39 P7 F11) [NBP2-66591] - Left and Center: Immunohistochemical staining of normal (left) and cancerous (center) colon tissue using TCP-1 beta antibody (Cat. No. NBP2-66591).Right: Western blot analysis using TCP-1 beta antibody on Calu6 (1) and HT-29 (2) cell lysates.

Applications for TCP1-beta Antibody (F39 P7 F11)

Application
Recommended Usage

Immunohistochemistry

5-10 ug/ml

Immunohistochemistry-Paraffin

1-5 ug/ml

Western Blot

1-2 ug/ml
Application Notes
.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Preservative

0.08% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: TCP1-beta

The protein TCP-1 (t-complex polypeptide 1) is a subunit of the hetero-oligomeric complex CCT (chaperonin containing TCP-1) present in the eukaryotic cytosol. The CCT of eukaryotic cytosol is composed of eight different subunit species that are proposed to have independent functions in folding its in vivo substrates, the Actins and Tubulins. TCP-1 was first identified in the mouse as relevant for tail-less and embryonic lethal phenotypes. Sequences homologous to TCP-1 have been isolated in several other species, and the yeast TCP-1 has been shown to encode a molecular chaperone for Actin and Tubulin. TCP-1 found in mammalian cells and yeast plays an important role in the folding of cytosolic proteins.

Alternate Names

Cctb, CCT-beta, CCTBPRO1633,99D8.1, chaperonin containing t-complex polypeptide 1, beta subunit, chaperonin containing t-complex polypeptide 1, subunit 2, chaperonin containing TCP1, subunit 2 (beta), MGC142074, MGC142076, T-complex protein 1 subunit beta, T-complex protein 1, beta subunit, TCP-1-beta

Gene Symbol

CCT2

UniProt

P47207 (C. elegans)

Additional TCP1-beta Products

Product Documents for TCP1-beta Antibody (F39 P7 F11)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for TCP1-beta Antibody (F39 P7 F11)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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