TCR V beta 12 Antibody (S511)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-22495

Novus Biologicals, part of Bio-Techne
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NBP2-22495
NBP2-22495-50ug
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Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen, Immunoprecipitation

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # S511

Concentration

0.12 mg/ml

View all TCR V beta 12 Antibodies »

Product Specifications

Immunogen

Human TCR V beta 12

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Applications for TCR V beta 12 Antibody (S511)

Application
Recommended Usage

Flow Cytometry

1 - 2 ug

Immunohistochemistry

1:10 - 1:500

Immunohistochemistry-Frozen

1:10 - 1:500

Immunoprecipitation

1:10 - 1:500

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS with 0.5% BSA

Preservative

0.1% Sodium Azide

Concentration

0.12 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: TCR V beta 12

The receptors on T cells consist of immunoglobulin like integral membrane glycoproteins containing 2 polypeptide subunits, alpha and beta, of similar molecular weight, 40 to 55 kD in the human. Like the immunoglobulins of the B cells, each T cell receptor subunit has, external to the cell membrane, an N terminal variable domain and a C terminal constant domain. T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex molecules at the surface of antigen presenting cells. Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci.

Alternate Names

T cell receptor beta locus, T-cell antigen receptor, beta polypeptide, T-cell receptor, beta cluster, T-cell receptor, beta cluster, TCRB, TRB

Entrez Gene IDs

6957 (Human)

Gene Symbol

TRB

UniProt

P04435 (Human)

Additional TCR V beta 12 Products

Product Documents for TCR V beta 12 Antibody (S511)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TCR V beta 12 Antibody (S511)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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