TCTN3 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-77183

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all TCTN3 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human TCTN3. The immunogen is located within amino acids 540 - 590 of TCTN3. Amino Acid Squence: TQKPQPPRGQPKMDWKW

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TCTN3 Antibody - BSA Free

Western Blot: TCTN3 AntibodyBSA Free [NBP1-77183]

Western Blot: TCTN3 AntibodyBSA Free [NBP1-77183]

Western Blot: TCTN3 Antibody [NBP1-77183] - HeLa cell lysate with TCTN3 antibody at (A) 1 and (B) 2ug/mL.
Immunocytochemistry/ Immunofluorescence: TCTN3 Antibody - BSA Free [NBP1-77183]

Immunocytochemistry/ Immunofluorescence: TCTN3 Antibody - BSA Free [NBP1-77183]

Immunocytochemistry/Immunofluorescence: TCTN3 Antibody [NBP1-77183] - HeLa cells with TCTN3 antibody at 20 ug/ml.
Immunocytochemistry/ Immunofluorescence: TCTN3 Antibody - BSA Free [NBP1-77183]

Immunocytochemistry/ Immunofluorescence: TCTN3 Antibody - BSA Free [NBP1-77183]

Immunocytochemistry/Immunofluorescence: TCTN3 Antibody [NBP1-77183] - HeLa cells with TCTN3 antibody at 4 ug/mL.

Applications for TCTN3 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Immunohistochemistry

4 ug/ml

Immunohistochemistry-Paraffin

4 ug/ml

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TCTN3

TCTN3 is a member of the Tectonic protein family, a group of evolutionarily conserved secreted and transmembrane proteins that regulate the Hedgehog (Hh)-mediated patterning of the neural tube. While the expression pattern and function of TCTN3 is not known, it is 58% similar to TCTN1. TCTN1 is expressed during embryonic development in regions that participate in Hh signaling, beginning in the gastrulation stages in the ventral node. Mice expressing mutant TCTN1 die between E13.5 and E16.5 and display holoprosencephaly, a defect associated with reduced Hh signaling, indicating the role of TCTN1 as an Hh activator. At later stages in development, TCTN1 is thought to also act as a repressor on the Hh pathway in the anterior and posterior neural tube.

Alternate Names

C10orf61, chromosome 10 open reading frame 61, DKFZP564D116, TECT3DKFZp564D116, tectonic 3, tectonic family member 3, tectonic-3

Gene Symbol

TCTN3

UniProt

NP_056446 (Human)

Additional TCTN3 Products

Product Documents for TCTN3 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TCTN3 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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