TDAG8/GPR65 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NLS1627

Novus Biologicals, part of Bio-Techne
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NLS1627
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Primate (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

View all TDAG8/GPR65 Antibodies »

Product Specifications

Immunogen

Synthetic 19 amino acid peptide from 3rd cytoplasmic domain of human TDAG8/GPR65.

Epitope

3rd cytoplasmic domain

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (95%), Marmoset (95%), Rabbit (84%).

Localization

Cell Membrane

Specificity

Human GPR65. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for TDAG8/GPR65 Antibody - BSA Free

Immunohistochemistry-Paraffin: TDAG8/GPR65 Antibody - BSA Free [NLS1627]

Immunohistochemistry-Paraffin: TDAG8/GPR65 Antibody - BSA Free [NLS1627]

Immunohistochemistry-Paraffin: TDAG8/GPR65 Antibody [NLS1627] - Human Lymph Node, Hodgkins Lymphoma tissue after heat-induced antigen retrieval.
Immunohistochemistry-Paraffin: TDAG8/GPR65 Antibody - BSA Free [NLS1627]

Immunohistochemistry-Paraffin: TDAG8/GPR65 Antibody - BSA Free [NLS1627]

Immunohistochemistry-Paraffin: TDAG8/GPR65 Antibody [NLS1627] - Analysis of anti-GPR65 / TDAG8 antibody with human lymph node, Hodgkins lymphoma.
Immunohistochemistry-Paraffin: TDAG8/GPR65 Antibody - BSA Free [NLS1627]

Immunohistochemistry-Paraffin: TDAG8/GPR65 Antibody - BSA Free [NLS1627]

Immunohistochemistry-Paraffin: TDAG8/GPR65 Antibody [NLS1627] - Human tonsil tissue after heat-induced antigen retrieval.

Applications for TDAG8/GPR65 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

9 - 23 ug/ml
Application Notes
.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: TDAG8/GPR65

GPR65 (TDAG8), a Lysophospholipid/Lysosphingolipid Receptor, is a molecular target for psychosine, a toxic lipid formed by the breakdown of galactosylceramide (cerebroside). A build-up of psychosine, caused by the lack of galactosylceramidase, results in the death of the myelin-synthesizing cells, oligodendrocytes, which is associated with Krabbe disease. GPR65 has been reported in human in peripheral blood leukocytes, spleen, lymph node, and thymus. ESTs have been isolated from human B-cell/lung/testis, brain/lung/testis, pancreas/spleen, lung/spleen, leukocyte, embryo, kidney, liver/spleen, thyroid, and vessel libraries.

Long Name

G Protein-coupled Receptor 65

Alternate Names

GPR65, Psychosine Receptor

Entrez Gene IDs

8477 (Human)

Gene Symbol

GPR65

UniProt

Q8IYL9 (Human)

Additional TDAG8/GPR65 Products

Product Documents for TDAG8/GPR65 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TDAG8/GPR65 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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