TDP-43/TARDBP [p Ser409, p Ser410] Antibody - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-16952

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Dot Blot, ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

Azide and BSA Free

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all TDP-43/TARDBP Antibodies »

Product Summary for TDP-43/TARDBP [p Ser409, p Ser410] Antibody - Azide and BSA Free

Immunogen

A synthetic phosphorylated peptide around S409 & S410 of human TDP-43/TARDBP (NP_031401.1). SKSSGW

Modification

p Ser 409, p Ser 410

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TDP-43/TARDBP [p Ser409, p Ser410] Antibody - Azide and BSA Free

Dot Blot: TDP-43/TARDBP [p Ser409, p Ser410] Antibody [NBP3-16952] - Dot-blot analysis of all sorts of peptides using TDP-43/TARDBP antibody (NBP3-16952) at 1:1000 dilution. Exposure time: 10s.
Dot Blot: TDP-43/TARDBP [p Ser409, p Ser410] Antibody [NBP3-16952] - Dot-blot analysis of all sorts of peptides using TDP-43/TARDBP antibody (NBP3-16952) at 1:1000 dilution. Exposure time: 1s.

Applications for TDP-43/TARDBP [p Ser409, p Ser410] Antibody - Azide and BSA Free

Application
Recommended Usage

Dot Blot

1:500 - 1:1000

Western Blot

1:500 - 1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 50% glycerol, pH7.3

Format

Azide and BSA Free

Preservative

0.05% Proclin 300

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: TDP-43/TARDBP

TARDBP, also known as TAR DNA binding protein, is a DNA and RNA-binding protein which regulates transcription and splicing. TARDBP is also involved in the regulation of CFTR splicing and promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. TARD-BP may also be involved in microRNA biogenesis, apoptosis and cell division. TARDBP can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat.

Long Name

TAR DNA-binding Protein 43

Alternate Names

ALS10, TARDBP, TDP43

Gene Symbol

TARDBP

Additional TDP-43/TARDBP Products

Product Documents for TDP-43/TARDBP [p Ser409, p Ser410] Antibody - Azide and BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TDP-43/TARDBP [p Ser409, p Ser410] Antibody - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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