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TFIIE-alpha Antibody (JE66-41)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-33006

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-33006

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # JE66-41

Concentration

1 mg/ml

Product Specifications

Immunogen

Synthetic peptide within Human TFIIE-alpha aa 390-439 / 439. (Uniprot: P29083)

Localization

Nucleus.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

49.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for TFIIE-alpha Antibody (JE66-41)

TFIIE-alpha Antibody (JE66-41)

Western Blot: TFIIE-alpha Antibody (JE66-41) [NBP3-33006]

Western Blot: TFIIE-alpha Antibody (JE66-41) [NBP3-33006] - Western blot analysis of TFIIE-alpha on different lysates with Rabbit anti-TFIIE-alpha antibody (NBP3-33006) at 1/1,000 dilution.

Lane 1: K-562 cell lysate (15 ug/Lane)
Lane 2: Jurkat cell lysate (15 ug/Lane)
Lane 3: Daudi cell lysate (15 ug/Lane)
Lane 4: HeLa cell lysate (15 ug/Lane)
Lane 5: A431 cell lysate (15 ug/Lane)
Lane 6: A549 cell lysate (15 ug/Lane)
Lane 7: HepG2 cell lysate (15 ug/Lane)
Lane 8: HEK-293 cell lysate (15 ug/Lane)
Lane 9: NIH/3T3 cell lysate (15 ug/Lane)
Lane 10: MCF7 cell lysate (15 ug/Lane)
Lane 11: Mouse testis tissue lysate (30 ug/Lane)
Lane 12: Rat testis tissue lysate (30 ug/Lane)

Predicted band size: 49.5 kDa
Observed band size: 60 kDa

Exposure time: 3 minutes;

4-20% SDS-PAGE gel.

Proteins were transferred to a PVDF membrane and blocked with 5% NFDM/TBST for 1 hour at room temperature. The primary antibody (NBP3-33006) at 1/1,000 dilution was used in 5% NFDM/TBST at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody at 1:100,000 dilution was used for 1 hour at room temperature.

Applications for TFIIE-alpha Antibody (JE66-41)

Application
Recommended Usage

Western Blot

1:1000

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

1*TBS (pH7.4), 0.05% BSA and 40% Glycerol

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TFIIE-alpha

Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase andDNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase

Alternate Names

FE, General transcription factor IIE 56 kDa subunit, general transcription factor IIE subunit 1, general transcription factor IIE, polypeptide 1 (alpha subunit, 56kD), general transcription factor IIE, polypeptide 1, alpha 56kDa, TF2E1, TFIIE-A, TFIIE-alpha, Transcription initiation factor IIE subunit alpha

Gene Symbol

GTF2E1

Additional TFIIE-alpha Products

Product Documents for TFIIE-alpha Antibody (JE66-41)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TFIIE-alpha Antibody (JE66-41)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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