TfR2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-17003

Novus Biologicals, part of Bio-Techne
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NBP3-17003-100ul
NBP3-17003-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all TfR2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: SVLVVSEDVNYEPDLDFHQGRLYWSDLQAMFLQFLGEGRLEDTIRQTSLRERVAGSAGMAALTQDIRAALSRQKLDHVWTDTHYVGLQFPDPAHPNTLHWVDEAGKVGEQLPLEDPDVYCPYS

Reactivity Notes

Mouse, Rat (80%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TfR2 Antibody

Immunohistochemistry-Paraffin: TfR2 Antibody [NBP3-17003]

Immunohistochemistry-Paraffin: TfR2 Antibody [NBP3-17003]

Immunohistochemistry-Paraffin: TfR2 Antibody [NBP3-17003] - Staining of human duodenum shows low expression as expected.
Immunohistochemistry-Paraffin: TfR2 Antibody [NBP3-17003]

Immunohistochemistry-Paraffin: TfR2 Antibody [NBP3-17003]

Immunohistochemistry-Paraffin: TfR2 Antibody [NBP3-17003] - Analysis in human liver and duodenum tissues using Anti-TFR2 antibody. Corresponding TFR2 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: TfR2 Antibody [NBP3-17003]

Immunohistochemistry-Paraffin: TfR2 Antibody [NBP3-17003]

Immunohistochemistry-Paraffin: TfR2 Antibody [NBP3-17003] - Staining of human liver shows high expression.

Applications for TfR2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TfR2

TFR2 is a gene that codes for a protein with three isoforms, with lengths of 801, 630, and 774 amino acids and weights of approximately 89, 70, and 86 kDa respectively. TFR2 helps in the cellular uptake of transferrin-bound iron as well as iron metabolism, erythrocyte differentiation, and hepatocyte function. Current studies are being done on several diseases and disorders related to this gene including porphyria cutanea tarda, iron overload, beta thalassemia, liver cirrhosis, hepatitis C, fatty liver disease, leukemia, lymphoma, liver disease, and cystic fibrosis. TRF2 has also been shown to have interactions with HFE, TF, UBC, and SOCS3 in pathways such as the AMPK enzyme complex and iron metabolism in the placenta pathways.

Long Name

Transferrin Receptor 2

Alternate Names

HFE3, TFRC2

Gene Symbol

TFR2

Additional TfR2 Products

Product Documents for TfR2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TfR2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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