Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry

Label

PE/Cy5.5 (Excitation = 488 nm, Emission = 695 nm)

Antibody Source

Monoclonal Mouse IgG2B Clone # 409522

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all TGR5/GPBAR1 Antibodies »

Product Specifications

Immunogen

NS0 mouse myeloma cell line transfected with human TGR5/GPBAR1
Met1-Asn330
Accession # Q8TDU6

Specificity

Stains human TGR5/GPBAR1 transfectants but not irrelevant transfectants.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Applications for TGR5/GPBAR1 Antibody (409522) [PE/Cy5.5]

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark. Do not freeze.

Background: TGR5/GPBAR1

TGR5, also called GPBAR1, M-BAR, or BG37 or is a G-protein coupled receptor superfamily member that is a widely expressed cell surface receptor for bile acids. On macrophages, bile acid engagement of TGR5/GPBAR1 suppresses phagocytosis and other functions. Extracellular portions of human TGR5/GPBAR1 show approximately 75% amino acid identity with corresponding regions of mouse TGR5/GPBAR1.

Long Name

Bile Acid Receptor TGR5

Alternate Names

BG37, GPBA, GPBAR1, GPCR19, GPR131, M-BAR

Gene Symbol

GPBAR1

Additional TGR5/GPBAR1 Products

Product Documents for TGR5/GPBAR1 Antibody (409522) [PE/Cy5.5]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for TGR5/GPBAR1 Antibody (409522) [PE/Cy5.5]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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