Thioredoxin Reductase 1/TRXR1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-55363

Novus Biologicals, part of Bio-Techne
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NBP2-55363
NBP2-55363-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (90%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Thioredoxin Reductase 1/TRXR1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: GFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVML

Reactivity Notes

Rat 86%

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Thioredoxin Reductase 1/TRXR1 Antibody

Western Blot: Thioredoxin Reductase 1/TRXR1 Antibody [NBP2-55363]

Western Blot: Thioredoxin Reductase 1/TRXR1 Antibody [NBP2-55363]

Western Blot: Thioredoxin Reductase 1/TRXR1 Antibody [NBP2-55363] - Western blot analysis in human cell line RT-4, human cell line U-251 MG, human plasma, human liver tissue and human tonsil tissue.
Immunocytochemistry/ Immunofluorescence: Thioredoxin Reductase 1/TRXR1 Antibody [NBP2-55363]

Immunocytochemistry/ Immunofluorescence: Thioredoxin Reductase 1/TRXR1 Antibody [NBP2-55363]

Immunocytochemistry/Immunofluorescence: Thioredoxin Reductase 1/TRXR1 Antibody [NBP2-55363] - Staining of human cell line U-251 MG shows localization to nucleoplasm & nucleoli fibrillar center.

Applications for Thioredoxin Reductase 1/TRXR1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Western Blot

0.04-0.4 ug/ml
Application Notes
ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Thioredoxin Reductase 1/TRXR1

thioredoxin reductase 1 is a pyridine nucleotide oxidoreductase which reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. It is thought to function as a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine residue which is required for the catalytic activity. Alternative splicing results in several transcript variants encoding the same protein. Additional transcript variants have been described but their biological validity has not been determined.

Alternate Names

GRIM-12, KDRF, TR1, TRXR1, TRXRD1, TXNR, TXNRD1

Gene Symbol

TXNRD1

Additional Thioredoxin Reductase 1/TRXR1 Products

Product Documents for Thioredoxin Reductase 1/TRXR1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Thioredoxin Reductase 1/TRXR1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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