Thioredoxin Reductase 1/TRXR1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-30194

Novus Biologicals, part of Bio-Techne
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NBP3-30194
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Key Product Details

Species Reactivity

Human

Applications

Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Thioredoxin Reductase 1/TRXR1 Antibodies »

Product Specifications

Immunogen

Between 125 and 175

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Thioredoxin Reductase 1/TRXR1 Antibody

Thioredoxin Reductase 1/TRXR1 Antibody

Immunoprecipitation:Thioredoxin Reductase 1/TRXR1 AntibodyNBP3-30194] -

Immunoprecipitation:Thioredoxin Reductase 1/TRXR1 AntibodyNBP3-30194] -Detection of human Thioredoxin Reductase 1 by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from HeLa cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-Thioredoxin Reductase 1 antibody NBP3-30194 (lot NBP3-30194-1) used for IP at 6 µg per reaction. Thioredoxin Reductase 1 was also immunoprecipitated by rabbit anti-Thioredoxin Reductase 1 antibody BL18351. For blotting immunoprecipitated Thioredoxin Reductase 1, NBP3-30194 was used at 1 µg/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

Applications for Thioredoxin Reductase 1/TRXR1 Antibody

Application
Recommended Usage

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

Tris-citrate/phosphate pH 7 -8.

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: Thioredoxin Reductase 1/TRXR1

thioredoxin reductase 1 is a pyridine nucleotide oxidoreductase which reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. It is thought to function as a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine residue which is required for the catalytic activity. Alternative splicing results in several transcript variants encoding the same protein. Additional transcript variants have been described but their biological validity has not been determined.

Alternate Names

GRIM-12, KDRF, TR1, TRXR1, TRXRD1, TXNR, TXNRD1

Gene Symbol

TXNRD1

Additional Thioredoxin Reductase 1/TRXR1 Products

Product Documents for Thioredoxin Reductase 1/TRXR1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Thioredoxin Reductase 1/TRXR1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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