THOC7 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-20622

Novus Biologicals, part of Bio-Techne
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NBP2-20622
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Bovine (100%), Chicken (90%), Rat (97%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all THOC7 Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human THOC7. The exact sequence is proprietary.

Reactivity Notes

Xenopus laevis (82%).

Localization

Cytoplasm; Nucleus

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

24 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for THOC7 Antibody

Western Blot: THOC7 Antibody [NBP2-20622]

Western Blot: THOC7 Antibody [NBP2-20622]

Western Blot: THOC7 Antibody [NBP2-20622] - Sample (50 ug of whole cell lysate) A: Mouse Brain, 15% SDS PAGE gel, diluted at 1:1000.
Immunocytochemistry/ Immunofluorescence: THOC7 Antibody [NBP2-20622]

Immunocytochemistry/ Immunofluorescence: THOC7 Antibody [NBP2-20622]

Immunocytochemistry/Immunofluorescence: THOC7 Antibody [NBP2-20622] - Immunofluorescence analysis of paraformaldehyde-fixed A431, using antibody at 1:200 dilution.
Western Blot: THOC7 Antibody [NBP2-20622]

Western Blot: THOC7 Antibody [NBP2-20622]

Western Blot: THOC7 Antibody [NBP2-20622] - Sample (30 ug of whole cell lysate) A: 293T B: A431 12% SDS PAGE gel, diluted at 1:1000.

Applications for THOC7 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol, 1% BSA

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: THOC7

Component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between THOC4 and the cap-binding protein NCBP1. UAP56 functions as a bridge between THOC4 and the THO complex. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. The recruitment of the TREX complex to the intronless viral mRNA occurs via an interaction between KSHV ORF57 protein and THOC4.

Alternate Names

FLJ23445, fSAP24NIF3L1-binding protein 1, Functional spliceosome-associated protein 24, Ngg1 interacting factor 3 like 1 binding protein 1, Ngg1-interacting factor 3-like protein 1-binding protein 1, NIF3L1BP1hTREX30, THO complex 7 homolog (Drosophila), THO complex subunit 7 homolog

Gene Symbol

THOC7

UniProt

Q6I9Y2 (Human)

Additional THOC7 Products

Product Documents for THOC7 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for THOC7 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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