Thromboxane A2 R/TBXA2R Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-31106

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (92%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Thromboxane A2 R/TBXA2R Antibodies »

Product Specifications

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Thromboxane A2 R/TBXA2R. The exact sequence is proprietary.

Localization

Cell membrane, Multi-pass membrane protein

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

37 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Thromboxane A2 R/TBXA2R Antibody

Western Blot: Thromboxane A2 R/TBXA2R Antibody [NBP1-31106]

Western Blot: Thromboxane A2 R/TBXA2R Antibody [NBP1-31106]

Western Blot: Thromboxane A2 R/TBXA2R Antibody [NBP1-31106] - Raji 12% SDS PAGE diluted at 1:500

Applications for Thromboxane A2 R/TBXA2R Antibody

Application
Recommended Usage

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Thromboxane A2 R/TBXA2R

The thromboxane A2 receptor (TBXA2R) is a member of the Prostanoid Receptor subfamily. TBXA2R performs an essential role in hemostasis by interacting with thromboxane A2 to induce platelet aggregation. Thromboxane A2 has been implicated in myocardial infarct, stroke, and asthma. Additionally, thromboxane-prostanoid receptors have been implicated in the pathogenesis of cardiovascular diseases. Changes in TBXA2R function have also been linked to a hereditary bleeding disorder. The thromboxane A2 receptor is encoded by a single gene that is alternatively spliced at the carboxyl terminus, resulting in two variants, TP (343 residues) and TP (407 residues) that share the first 328 amino acids.

Long Name

Thromboxane A2 Receptor

Alternate Names

BDPLT13, Prostanoid TP Receptor, TBXA2R, Thromboxane A2R, TP, TXA2R2

Entrez Gene IDs

6915 (Human)

Gene Symbol

TBXA2R

UniProt

P21731 (Human)

Additional Thromboxane A2 R/TBXA2R Products

Product Documents for Thromboxane A2 R/TBXA2R Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Thromboxane A2 R/TBXA2R Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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