Thymidylate Synthase Antibody (2B2)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-15154

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-15154
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 2B2

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Thymidylate Synthase Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human Thymidylate Synthase. UniProt ID (P04818).

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Thymidylate Synthase Antibody (2B2)

Western Blot: Thymidylate Synthase Antibody (2B2) [NBP3-15154]

Western Blot: Thymidylate Synthase Antibody (2B2) [NBP3-15154]

Western Blot: Thymidylate Synthase Antibody (2B2) [NBP3-15154] - Positive WB detected in: Hela whole cell lysate, 293T whole cell lysate, 293 whole cell lysate, Jurkat whole cell lysate, HepG2 whole cell lysate, HL-60 whole cell lysate. All lanes: Thymidylate Synthase antibody at 1:2000. Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 36, 32, 27 KDa. Observed band size: 36 KDa.

Applications for Thymidylate Synthase Antibody (2B2)

Application
Recommended Usage

Western Blot

1:500-1:5000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 150mM NaCl, and 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -80C. Avoid freeze-thaw cycles.

Background: Thymidylate Synthase

Thymidylate synthase (TS) is an intracellular enzyme critical for de novo synthesis of DNA. In cancer, expression of TS is often elevated and becomes further elevated as a result of treatment with the most commonly used chemotherapeutic, 5-fluorouracil (5-FU). Resistance or lack of response to 5-FU is attributed to the elevation of TS activity. Overexpression of TS has been demonstrated in many types of tumors including breast, colon, gastric and melanoma and is usually predictive of shortened survival time.

Long Name

Thymidylate synthase

Alternate Names

EC 2.1.1.45, OK/SW-cl.29, TS, TSase, TYMS

Gene Symbol

TYMS

Additional Thymidylate Synthase Products

Product Documents for Thymidylate Synthase Antibody (2B2)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Thymidylate Synthase Antibody (2B2)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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