Thymopoietin/LAP2 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-81736

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Rat (95%). Backed by our 100% Guarantee.

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all Thymopoietin Antibodies »

Product Specifications

Immunogen

Thymopoietin antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human Thymopoietin. The immunogen is located within amino acids 80 - 130 of Thymopoietin. Amino Acid Squence: CVGRKATKKTDKPRQEDKDD

Specificity

At least three isoforms of Thymopoietin/LAP2 are known to exist; this antibody will detect all isoforms. Thymopoietin/LAP2 antibody is predicted to not cross-react with other LEM domain-containing proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Thymopoietin/LAP2 Antibody - BSA Free

Western Blot: Thymopoietin/LAP2 AntibodyBSA Free [NBP2-81736]

Western Blot: Thymopoietin/LAP2 AntibodyBSA Free [NBP2-81736]

Western Blot: Thymopoietin/LAP2 Antibody [NBP2-81736] - Analysis of Thymopoietin/LAP2 in HeLa cell lysate with Thymopoietin/LAP2 antibody at 0.25 ug/ml in (A) the absence and (B) the presence of blocking peptide.
Immunocytochemistry/ Immunofluorescence: Thymopoietin/LAP2 Antibody - BSA Free [NBP2-81736]

Immunocytochemistry/ Immunofluorescence: Thymopoietin/LAP2 Antibody - BSA Free [NBP2-81736]

Immunocytochemistry/Immunofluorescence: Thymopoietin/LAP2 Antibody [NBP2-81736] - Immunofluorescence of Thymopoietin/LAP2 in HeLa cells with Thymopoietin/LAP2 antibody at 5 ug/mL.
Immunocytochemistry/ Immunofluorescence: Thymopoietin/LAP2 Antibody - BSA Free [NBP2-81736]

Immunocytochemistry/ Immunofluorescence: Thymopoietin/LAP2 Antibody - BSA Free [NBP2-81736]

Immunocytochemistry/Immunofluorescence: Thymopoietin/LAP2 Antibody [NBP2-81736] - Immunocytochemistry of Thymopoietin/LAP2 in HeLa cells with Thymopoietin/LAP2 antibody at 2.5 ug/mL.
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Applications for Thymopoietin/LAP2 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

2.5-5 ug/ml

Western Blot

0.25 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Thymopoietin

Lamins are type V intermediate filament proteins and are grouped into constitutively expressed B-type lamins and developmentally regulated A-type lamins. Lamin-binding proteins in the nuclear lamina and the nuclear interior include several protein families and/or types of proteins in higher eukaryotes such as the inner nuclear membrane proteins, lamin B receptor, emerin, and MANI, three isoforms of lamina-associated polypeptide 1 (LAP 1), and several isoforms of LAP 2. Up to six LAP 2 isoforms derive from a single gene by alternative splicing in mammals and various isoforms have been described in Xenopus. The best characterized LAP2 isoforms are the inner nuclear membrane protein LAP 2 beta and the nucleoplasmic protein LAP 2 alpha, which are identical in their N-terminal 187-amino acid constant region but differ in their C termini. While LAP 2 beta binds to B-type lamins at the nuclear periphery and was suggested to regulate nuclear lamina growth , LAP 2 alpha specifically interacts with A-type lamins within the nuclear interior as part of a detergent/salt-resistant nucleoskeletal structure.

Alternate Names

TMPO

Gene Symbol

TMPO

Additional Thymopoietin Products

Product Documents for Thymopoietin/LAP2 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Thymopoietin/LAP2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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