Thyroid receptor-interacting protein 11 Antibody (10G5)

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-41204

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 10G5

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Thyroid receptor-interacting protein 11 Antibodies »

Product Specifications

Immunogen

Amino acids 1099-1372 of Thyroid receptor-interacting protein 11 expressed in E. coli.

Specificity

This antibody will recognize human TRIP230.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

228 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Thyroid receptor-interacting protein 11 Antibody (10G5)

Immunocytochemistry/ Immunofluorescence: Thyroid receptor-interacting protein 11 Antibody (10G5) [NBP1-41204]

Immunocytochemistry/ Immunofluorescence: Thyroid receptor-interacting protein 11 Antibody (10G5) [NBP1-41204]

Immunocytochemistry/Immunofluorescence: Thyroid receptor-interacting protein 11 Antibody (10G5) [NBP1-41204] - Analysis of methanol-fixed HeLa, using antibody at 1:100 dilution.

Applications for Thyroid receptor-interacting protein 11 Antibody (10G5)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Assay dependent

Immunoprecipitation

Assay dependent

Western Blot

1:500
Application Notes
ICC/IF, IP Assay dependent

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Thyroid receptor-interacting protein 11

The Trip230 gene encodes a protein of 1,978 amino acids with an estimated molecular mass of 230 kDa. The gene is located on chromosome 14q31, which is in a region associated with genetic alterations and thyroid hormone response abnormalities. The Trip230 protein interacts with Rb and thyroid hormone receptor (TR) using two distinct domains. Complex formation with Rb is in a hormone independent manner, but when Trip230 forms a complex with TR, it is in a thyroid hormone-dependent manner. After T3 treatment, Trip230 is phosphorylated and transported to the nucleus, suggesting that phosphorylation may be important for its nuclear translocation.

Alternate Names

CEV14TR-interacting protein 11, Clonal evolution-related gene on chromosome 14 protein, GMAP-210ACG1A, Golgi-associated microtubule-binding protein 210, Golgi-microtubule-associated protein of 210 kDa, thyroid hormone receptor interactor 11, thyroid receptor-interacting protein 11, TRIP-11, Trip230

Entrez Gene IDs

9321 (Human)

Gene Symbol

TRIP11

Additional Thyroid receptor-interacting protein 11 Products

Product Documents for Thyroid receptor-interacting protein 11 Antibody (10G5)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Thyroid receptor-interacting protein 11 Antibody (10G5)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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