TIA1 Antibody (TRIA1-1)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-27932

Novus Biologicals, part of Bio-Techne
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NBP3-27932
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Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # TRIA1-1

Concentration

0.2 mg/ml

View all TIA1 Antibodies »

Product Specifications

Immunogen

Human partial recombinant protein (amino acids 279-380) was used as the immunogen for this TIA1 antibody.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Scientific Data Images for TIA1 Antibody (TRIA1-1)

TIA1 Antibody (TRIA1-1)

Western Blot: TIA1 Antibody (TRIA1-1) [NBP3-27932] -

Western Blot: TIA1 Antibody (TRIA1-1) [NBP3-27932] - Western blot testing of A) HepG2, B) PC3 and C) HeLa cell lysate wiht TIA1 antibody (clone TRIA1-1). The long and short forms differ by 17 amino acids. Predicted molecular weight: ~43kDa and ~15kDa (granulocyte-associated isoform).
TIA1 Antibody (TRIA1-1)

Western Blot: TIA1 Antibody (TRIA1-1) [NBP3-27932] -

Western Blot: TIA1 Antibody (TRIA1-1) [NBP3-27932] - Western blot testing of A) HepG2, B) PC3 and C) HeLa cell lysate wiht TIA1 antibody (clone TRIA1-1). The long and short forms differ by 17 amino acids. Predicted molecular weight: ~43kDa and ~15kDa (granulocyte-associated isoform).

Applications for TIA1 Antibody (TRIA1-1)

Application
Recommended Usage

Western Blot

1 - 2 ug/mL

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS, 0.1 mg/ml BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TIA1

The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature.

Alternate Names

cytotoxic granule-associated RNA-binding protein, nucleolysin TIA-1 isoform p40, p40-TIA-1, p40-TIA-1 (containing p15-TIA-1), RNA-binding protein TIA-1, T-cell-restricted intracellular antigen-1, TIA-1, TIA1 cytotoxic granule-associated RNA binding protein, TIA1 cytotoxic granule-associated RNA-binding protein

Gene Symbol

TIA1

UniProt

P31483 (Human)

Additional TIA1 Products

Product Documents for TIA1 Antibody (TRIA1-1)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TIA1 Antibody (TRIA1-1)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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