TIAM2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-80713

Novus Biologicals, part of Bio-Techne
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NBP1-80713
NBP1-80713-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Rat, Bovine

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

IF/IHC, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all TIAM2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: IKESDILSDEDDDHRQTVKQGSPTKDIEIQFQRLRISEDPDVHPEAEQQPGPESGEGQKGGEQPKLVRGHFCPIKRKANSTKRDRGTLLKAQIRHQSLDSQSENATIDLNSVL

Reactivity Notes

Reactivity reported in scientific literature (PMID: 25646088)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TIAM2 Antibody

Immunocytochemistry/ Immunofluorescence: TIAM2 Antibody [NBP1-80713]

Immunocytochemistry/ Immunofluorescence: TIAM2 Antibody [NBP1-80713]

Immunocytochemistry/Immunofluorescence: TIAM2 Antibody [NBP1-80713] - Staining of human cell line A-431 shows localization to nucleoplasm.
Immunohistochemistry-Paraffin: TIAM2 Antibody [NBP1-80713]

Immunohistochemistry-Paraffin: TIAM2 Antibody [NBP1-80713]

Immunohistochemistry-Paraffin: TIAM2 Antibody [NBP1-80713] - Staining of human cerebral cortex shows strong positivity in neuropil.

Applications for TIAM2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TIAM2

TIAM2 encodes a guanine nucleotide exchange factor. A highly similar mouse protein specifically activates ras-related C3 botulinum substrate 1, converting this Rho-like guanosine triphosphatase (GTPase) from a guanosine diphosphate-bound inactive state to a guanosine triphosphate-bound active state. The encoded protein may play a role in neural cell development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]

Alternate Names

FLJ41865, KIAA2016, SIF and TIAM1-like exchange factor, STEFTIAM-2, T-cell lymphoma invasion and metastasis 2, T-lymphoma invasion and metastasis-inducing protein 2

Entrez Gene IDs

26230 (Human)

Gene Symbol

TIAM2

Additional TIAM2 Products

Product Documents for TIAM2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TIAM2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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